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Found 2639 clinical trials
Featured trial
The Neureka Project

The Neureka Project aims to develop new ways of detecting disorders of the brain early. From mental health conditions to dementia, we want to find out who is at risk and why, so we can develop preventative interventions that can be used the world over. To do this, we are taking …

Online studies
  • 5746 views
  • 28 Sep, 2022
  • 1 location
  • Online study
Featured trial
Caregiver-Provided Life Review for Persons with Dementia

>mild depressive symptoms who are 65 years or older, community-dwellers or the residents of senior housing, independent or assisted living facilities conducted by their family members

Accepts healthy volunteers
dementia
Online studies
depression
  • 658 views
  • 23 Sep, 2022
  • 1 location
  • Online study
Featured trial
Assessing Suicide Risk in the Context of Subjective Cognitive Decline

We are conducting a study to learn more about health factors that may increase or decrease risk for suicide for people 60 years and older with Subjective Cognitive Decline (experiencing recent changes in memory or other thinking processes but do not have a diagnosed neurocognitive disorder). Eligible participants will meet …

Online studies
Accepts healthy volunteers
  • 747 views
  • 15 Nov, 2022
  • 1 location
  • Online study
Featured trial
Pain Sensitivity and Unpleasantness in People with Alzheimer’s Disease and/or Cancer

The University of Tennessee Health Science Center in Memphis, TN has a research opportunity for people to participate in the study: Pain Sensitivity and Unpleasantness in People with Alzheimer’s Disease and Cancer. Specifically, they are looking for individuals over the age of 60 for 1 of 3 groups: (1) those …

primary cancer
Online studies
AIDS
cancer
  • 41 views
  • 28 Sep, 2022
  • 1 location
  • Online study
Featured trial
Preventing Alzheimer's With Cognitive Training (PACT)

Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and …

dementia
cognitive stimulation
Accepts healthy volunteers
cognitive impairment
mild cognitive impairment
  • 1 views
  • 28 Oct, 2022
  • 5 locations
Featured trial
Cognitive Fitness for Depression in Older Adults

This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with

  • 85 views
  • 22 Jan, 2022
  • 1 location
Featured trial
Ketamine for the Treatment of Depression in Parkinson's Disease (KET-PD)

The main purpose of this study is to examine the efficacy and safety of a repeated dosing ketamine infusion paradigm compared to placebo in individuals with PD. A subset of participants in each arm will undergo baseline and post-treatment PET and fMRI scans, to examine whether changes in synaptic density …

depressive disorder
depressed mood
hoehn and yahr scale
depression
ketamine
  • 41 views
  • 07 Oct, 2022
  • 1 location
Featured trial
Methodology Issues in a Tailored Light Treatment for Persons With Dementia

Tailored light treatment will increase sleep efficiency, reduce depression and reduce agitation scores in those with Alzheimer's disease and related dementia

mini-mental state examination
depressed mood
Accepts healthy volunteers
mental state examination
agitation
  • 6 views
  • 01 Apr, 2022
  • 2 locations
Featured trial
A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (LIGHTHOUSE)

score means more severe PD symptoms. Part I assesses non-motor experiences of daily living, including but not limited to memory loss, problems sleeping, pain, depression, and anxiety.

hoehn and yahr scale
movement disorder
depression
motor symptoms
  • 1 views
  • 16 Nov, 2022
  • 2 locations
Featured trial
Dementia Family Caregiver Study

The proposed study will test a 3-month, community health worker (CHW) delivered home visit, culturally and language-appropriate intervention for ethnic and underserved dementia family caregivers of persons with dementia (PWD) using wearable technology for real time monitoring of caregivers' stress and sleep. The CHW delivered home visit intervention includes stress …

alzheimer's disease
Accepts healthy volunteers
  • 27 views
  • 30 Apr, 2022
  • 1 location