Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 421 clinical trials
Featured trial
Ketamine for the Treatment of Depression in Parkinson's Disease (KET-PD)

The main purpose of this study is to examine the efficacy and safety of a repeated dosing ketamine infusion paradigm compared to placebo in individuals with PD.

ketamine
depressive disorder
hoehn and yahr scale
depression
depressed mood
  • 6 views
  • 12 May, 2022
  • 1 location
Featured trial
Cognitive Fitness for Depression in Older Adults

This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance …

  • 36 views
  • 22 Jan, 2022
  • 1 location
Featured trial
Depression

> Research is needed to find new, more effective, faster-acting treatment options with fewer side effects. People with MDD experience a depressed mood (persistent feelings of sadness

suicidal
depressive disorder
depressive symptoms
transcranial magnetic stimulation
treatment resistant depression
  • 61 views
  • 30 Jul, 2021
  • 1 location
Featured trial
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder

A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder

  • 112 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Clinical trial measuring efficacy of Vortioxetine for relapse prevention in adults with MDD

Clinical trial measuring efficacy of Vortioxetine for relapse prevention in adults with MDD

  • 100 views
  • 23 Nov, 2020
  • 1 location
Valuation in Depressed Mood, Anhedonia, and Anxiety

This study examines how people respond to rewards and losses, and the extent to which these responses are linked or distinct among people experiencing depressed mood, anhedonia, and/or anxiety

  • 0 views
  • 23 May, 2022
  • 1 location
The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement (CRC289A07)

(fully crossed 2x2 placebo design) before performing a probabilistic reinforcement learning task, an effort expenditure task, and undergo a depressed mood induction procedure. Further, EEG indices will

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
Translational Model of Anhedonia

The proposed research addresses a major mental health issue (anhedonia) with a novel computationally-inspired translational technique in both humans and mice. This approach greatly increases the likelihood that a positive animal model result will be successfully translated to humans. This research plan thus offers a novel way to address the …

Accepts healthy volunteers
  • 7 views
  • 21 Feb, 2022
  • 1 location
Comparison of Pilates and Conventional Treatment in Addition to Pilates in Patients With Chronic Neck Pain

The aim of this study is to investigate the effects of clinical pilates exercises and electrotherapy on pain level, physical condition, functional status and psychosocial status in patients with chronic neck pain.In the study, individuals will be divided into two groups. Pilates will be applied to one group for 6 …

  • 0 views
  • 25 Mar, 2022
The Sub-Saharan Africa Regional Partnership for Mental Health Capacity Building (SHARP)

The investigators will conduct an implementation science research study that will compare two different implementation strategies to facilitate ongoing Ministry of Health efforts to scale up depression treatment within non-communicable diseases clinics, as well as assessing clinic-related factors that will influence uptake.

antidepressants
depressed mood
depressive symptoms
  • 0 views
  • 09 Feb, 2022
  • 11 locations