depressed mood Clinical Research Trials

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Found 398 clinical trials

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Depression Study

758 views
23 Nov, 2020
1 location

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A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder

100 views
23 Nov, 2020
1 location

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Clinical trial measuring efficacy of Vortioxetine for relapse prevention in adults with MDD

100 views
23 Nov, 2020
1 location

Improving Cognition Via Exercise in Schizophrenia

People with schizophrenia display a broad range of cognitive impairments that have been identified as major determinants of poor functioning and disability. Also, people with schizophrenia are at increased risk for suicide, with approximately 40-50% of individuals attempting to take their own lives during their lifetime. The goal of the …

12 views
24 Jan, 2021
4 locations

Translational Model of Anhedonia

The proposed research addresses a major mental health issue (anhedonia) with a novel computationally-inspired translational technique in both humans and mice. This approach greatly increases the likelihood that a positive animal model result will be successfully translated to humans. This research plan thus offers a novel way to address the …

7 views
23 Jan, 2021
1 location

Smoking Cessation Program in the Preadmission Clinic

This study is a randomized, double-blind, placebo-controlled clinical trial which evaluates the efficacy of preoperative smoking counseling and varenicline (a medication approved by Health Canada and FDA for quitting smoking) to provide long term smoking cessation (i.e., abstinence for at least one year) in surgical patients. The primary hypothesis is …

106 views
08 Nov, 2020
1 location

Adolescent Depression Associated With Parental Depression

Depression is difficult to identify, prevent and treat in adolescents because of complex and stigmatized multiform symptoms and pathways of care. In children the existence of a parental depression is a significant and recognized risk factor for the development of a depression. It is regularly reported that 30% of adolescents …

depressed mood

11 views
03 Feb, 2021
24 locations

Enhancing the Clinical Effectiveness of Depression Screening Using Patient-targeted Feedback in General Practices

The multi-center GET.FEEDBACK.GP randomized controlled trial is designed based on patients' needs and preferences. In order to evaluate the effect of feedback in the broader setting of primary care, a total of 1076 primary care patients with elevated levels of depression (PHQ-9 score 10) will be randomized into three groups …

depressed mood

depression screening

0 views
27 Jan, 2021
2 locations

PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents

The study is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental health disorders. Using cluster …

depressed mood

behavior therapy

depressive symptoms

psychiatric disorder

depressive disorder

32 views
23 Jan, 2021
1 location

Personalized Prevention of Depression in Primary Care

The main goal is to design, develop and evaluate a personalized intervention to prevent the onset of depression based on Information and Communications Technology (ICTs), risk predictive algorithms and decision support systems (DSS) for patients and general practitioners (GPs). The specific goals are 1) to design and develop a DSS, …

major depressive disorder

depressed mood

anxiety

0 views
24 Jan, 2021
8 locations

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Found 398 clinical trials