Found 414 clinical trials
Cognitive Fitness for Depression in Older Adults
This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance …
- 0 views
- 23 Mar, 2021
- 1 location
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder
- 100 views
- 23 Nov, 2020
- 1 location
Clinical trial measuring efficacy of Vortioxetine for relapse prevention in adults with MDD
Clinical trial measuring efficacy of Vortioxetine for relapse prevention in adults with MDD
- 100 views
- 23 Nov, 2020
- 1 location
Treating Depressed Mood With a Smartphone-delivered Positive Word Stimulation for Subthreshold Depression
investigate the immediate effects of SPSRS applications on depressed mood in people with StD.
- 0 views
- 10 Mar, 2021
- 1 location
Improving Cognition Via Exercise in Schizophrenia
People with schizophrenia display a broad range of cognitive impairments that have been identified as major determinants of poor functioning and disability. Also, people with schizophrenia are at increased risk for suicide, with approximately 40-50% of individuals attempting to take their own lives during their lifetime. The goal of the …
- 12 views
- 24 Jan, 2021
- 4 locations
Translational Model of Anhedonia
The proposed research addresses a major mental health issue (anhedonia) with a novel computationally-inspired translational technique in both humans and mice. This approach greatly increases the likelihood that a positive animal model result will be successfully translated to humans. This research plan thus offers a novel way to address the …
- 7 views
- 03 May, 2021
- 1 location
Smoking Cessation Program in the Preadmission Clinic
This study is a randomized, double-blind, placebo-controlled clinical trial which evaluates the efficacy of preoperative smoking counseling and varenicline (a medication approved by Health Canada and FDA for quitting smoking) to provide long term smoking cessation (i.e., abstinence for at least one year) in surgical patients. The primary hypothesis is …
- 106 views
- 08 Nov, 2020
- 1 location
The Sub-Saharan Africa Regional Partnership for Mental Health Capacity Building
The investigators will conduct an implementation science research study that will compare two different implementation strategies to facilitate ongoing Ministry of Health efforts to scale up depression treatment within non-communicable diseases clinics, as well as assessing clinic-related factors that will influence uptake.
- 0 views
- 04 Jun, 2021
- 12 locations
A Study of the Change in Disease State and Safety of Oral Cariprazine Capsules in the Treatment of Depression in Pediatric Participants (10 to 17 Years of Age) With Bipolar I Disorder
Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of bipolar disorder in the pediatric population has not been as widely studied as the treatment of …
- 0 views
- 21 Jun, 2021
- 63 locations