Found 430 clinical trials
Cognitive Fitness for Depression in Older Adults
This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance …
- 0 views
- 23 Mar, 2021
- 1 location
Depression
> Research is needed to find new, more effective, faster-acting treatment options with fewer side effects. People with MDD experience a depressed mood (persistent feelings of sadness
- 16 views
- 30 Jul, 2021
- 1 location
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder
- 100 views
- 23 Nov, 2020
- 1 location
Clinical trial measuring efficacy of Vortioxetine for relapse prevention in adults with MDD
Clinical trial measuring efficacy of Vortioxetine for relapse prevention in adults with MDD
- 100 views
- 23 Nov, 2020
- 1 location
Treating Depressed Mood With a Smartphone-delivered Positive Word Stimulation for Subthreshold Depression
investigate the immediate effects of SPSRS applications on depressed mood in people with StD.
- 0 views
- 10 Mar, 2021
- 1 location
Improving Cognition Via Exercise in Schizophrenia
People with schizophrenia display a broad range of cognitive impairments that have been identified as major determinants of poor functioning and disability. Also, people with schizophrenia are at increased risk for suicide, with approximately 40-50% of individuals attempting to take their own lives during their lifetime. The goal of the …
- 12 views
- 24 Jan, 2021
- 4 locations
Translational Model of Anhedonia
The proposed research addresses a major mental health issue (anhedonia) with a novel computationally-inspired translational technique in both humans and mice. This approach greatly increases the likelihood that a positive animal model result will be successfully translated to humans. This research plan thus offers a novel way to address the …
- 7 views
- 03 May, 2021
- 1 location
Smoking Cessation Program in the Preadmission Clinic
This study is a randomized, double-blind, placebo-controlled clinical trial which evaluates the efficacy of preoperative smoking counseling and varenicline (a medication approved by Health Canada and FDA for quitting smoking) to provide long term smoking cessation (i.e., abstinence for at least one year) in surgical patients. The primary hypothesis is …
- 106 views
- 08 Nov, 2020
- 1 location
ODYSSEE-vCHAT Pilot Trial for Chronic Heart Failure
INTRODUCTION Psychological distress and reduced quality of life are prevalent in patients with chronic heart failure (CHF). The one-year rehospitalization rate is very high (40%), as well as the five-year mortality rates (45% for women and 60% for men). International task force committees report that medical therapy combined with digital …
- 0 views
- 23 Aug, 2021
- 3 locations