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Found 14 clinical trials
Featured trial
Interactive Effects of Periodontitis, the Gut Microbiome, and ApoE4 in Alzheimer’s Disease

This study is looking for people over the age of 65. The study is interested in the possible relationship between gum disease, gut health, and cognition.

  • 60 views
  • 13 Nov, 2020
  • 1 location
None
Older Adult Effectiveness of 2 Treatments

The study is a cluster randomized clinical trial (RCT) to be conducted in 22 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs in NE Ohio. The facilities will be randomized to 2 arms: Arm 1 (11 sites) - Participants will receive biannual silver diamine fluoride …

arrest
fluoride
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

pre-anesthesia evaluation Recipients will have: Lung test, heart tests, radiology scans, CT scans, and dental exam Possible tissue biopsies or lumbar puncture Bone marrow

lymphoma
immunodeficiency
electrocardiogram
vasculitis
bone marrow procedure
  • 439 views
  • 19 Oct, 2021
  • 2 locations
None
Arrest of Proximal Caries Using Orthodontic Bands and Glass Ionomer Cement

The purpose of this study is to evaluate the efficacy of using orthodontic bands with glass ionomer cement to arrest or reverse interproximal lesions as a preventive treatment compared to monitoring and oral hygiene. The investigators hypothesize that placing orthodontic bands with glass ionomer cement will arrest and possibly remineralize …

  • 0 views
  • 12 Sep, 2021
  • 2 locations
None
Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children

This is an investigator initiated randomized double-blind pilot study at the UCSF Pediatric Dental Clinics to compare effectiveness of a new toothpaste Livionex Dental Gel with a standard children's toothpaste containing 1500 ppm fluoride in reducing dental plaque and caries in healthy and well children every 3 months for 9 …

dental plaque
fluoride
  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

The goal of this clinical research study is to compare the use of MRI simulations to plan different doses of intensity modulated radiotherapy (IMRT) to the standard IMRT dose in patients with low risk human papilloma virus positive oropharyngeal cancer. This is an investigational study. MRI simulations and radiation therapy …

cancer
immunohistochemistry
carcinoma
oropharyngeal carcinoma
oropharyngeal squamous cell carcinoma
  • 9 views
  • 23 Jan, 2021
  • 1 location
None
Randomized Trial of Intensity-Modulated Proton Beam Therapy (IMPT) Versus Intensity-Modulated Photon Therapy (IMRT) for the Treatment of Oropharyngeal Cancer of the Head and Neck

The goal of this clinical research study is to compare the side effects of 2 radiation treatments for head and neck cancer. The 2 treatments are intensity modulated photon therapy (IMRT) and intensity modulated proton therapy (IMPT). Participants will also receive chemotherapy along with radiation therapy. IMPT is designed to …

carcinoma
concurrent chemotherapy
oropharyngeal
squamous cell carcinoma
intensity-modulated radiation therapy
  • 41 views
  • 13 Apr, 2021
  • 11 locations
None
Tooth and Tissue Sample Collection During Wisdom Teeth Removal

>Participants will be screened with a physical exam and medical history. A full dental exam with x-rays will be given to evaluate the need for surgery. At the second visit, participants will have

dental exam
oral surgery
Accepts healthy volunteers
tooth extraction
dental caries
  • 57 views
  • 24 Oct, 2021
  • 1 location
None
Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

dental exam, including dental x-rays and photos. The study visit will involve collection of blood, urine, and other samples, including saliva, plaque, and gum swabs. Any abnormal tissue will

tooth loss
Accepts healthy volunteers
periodontitis
severe periodontal disease
osteopenia
  • 169 views
  • 24 Oct, 2021
  • 1 location
None
BBD Longitudinal Study of Osteogenesis Imperfecta

Osteogenesis Imperfecta (OI) is a rare disorder that causes bones to break easily. People with OI may have broken bones with little or no trauma, dentinogenesis imperfecta (DI), and, in adult years, hearing loss. It is seen in both genders and all races. OI can range from very severe to …

dental exam
bone disease
col1a2
dentinogenesis imperfecta
hearing loss
  • 113 views
  • 24 Jan, 2021
  • 10 locations