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Found 66 clinical trials
Quality of Life in Women With X-linked Adrenoleukodystrophy (X-ALD_QoL)

phenotype is adrenomyeloneuropathy (AMN), a slowly progressive myelopathic variant with demyelination of the long tracts in the spinal cord, clinically manifested as slowly progressive spastic paraparesis

  • 21 Apr, 2022
  • 1 location
Assessing Neuroinflammation in GWI Using MRS

The primary aim of this study is to determine if Gulf War Illness (GWI) likely involves neuroinflammation. The investigators hypothesize that GWI involves neuroinflammation. By assessing the five neuroinflammatory outcomes across the brain, the investigators can determine if there are focal or global signs of one or more neuroinflammatory markers …

Accepts healthy volunteers
  • 11 Mar, 2022
  • 1 location
Evaluation of the Diagnostic Contributions of Nerve Ultrasound in Chronic Inflammatory Demyelinating Polyneuropathy Associating Systemic Diseases (CIDP Echo-nerf) (CIDP echo-nerf)

Chronic inflammatory demyelinating polyradiculoneuritis (CIDP) is an autoimmune disorder of the peripheral nervous system, most commonly affecting the myelin sheath. The pathophysiology of CIDP is not completely understood, but both humoral and cellular immunity appear to be involved in the genesis of this disease. Some diseases are particularly associated with …

type 2 diabetes
  • 06 May, 2022
  • 1 location
The Norwegian Study of Nervous System Manifestations and Sequelae After COVID-19

Neurologic, neuropsychological and neuropsychiatric symptoms, signs and diagnoses are increasingly being reported in COVID-19 patients. However, the extent and implications of such "NeuroCOVID" involvement, as well as blood and MRI biomarkers for neurological and psychiatric COVID-19-affection and treatments, warrants further studies. The investigator will perform a national study with clinical …

  • 13 Mar, 2021
  • 15 locations
Hizentra® in Inflammatory Neuropathies - pHeNIx Study (pHeNIx)

The pHeNIx study, a national multicentre prospective non-interventional study, should help to describe the conditions of use for Hizentra® and the methods for switching from the IV to SC route in everyday practice, together with the tolerability and efficacy of treatment, which is monitored using a patient application (PRO: Patient-Reported …

inflammatory neuropathy
immune globulin
  • 13 Jul, 2022
  • 11 locations
The Reliability of the Nine Hole Peg Test in Patients With Multiple Sclerosis

The main aim of the project is to establish inter-rater reliability, internal variability and variability of results got in two different ways of the Nine Hole Peg Test administered according to the new Czech extended version manual in patients with multiple sclerosis.

  • 04 Oct, 2021
  • 2 locations
A Registered Cohort Study of Immune-Mediated Neuropathies

This study will provide further insights into the natural course of the disease about Immune-Mediated Neuropathies including clinical featuresprogression, related antibody spectrum and drug treatment effect.

  • 05 Jan, 2022
  • 2 locations
Ccf mtDNA as a Neurodegenerative Biomarker

There is a long history of research into body fluid biomarkers in neurodegenerative and neuroinflammatory diseases. However, only a few biomarkers in cerebrospinal fluid (CSF) are being used in clinical practice. One of the most critical factors in biomarker research is the inadequate linkage of biological samples with data from …

multiple sclerosis
Accepts healthy volunteers
  • 16 May, 2022
  • 1 location
Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis

This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which we believe is detrimental to MS. We will examine clinical data (MRI, lab results, medical history, labs, and sleep studies) of Dr. Sloane's MS patients. …

  • 26 Jan, 2021
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research. We make it easy for patients to contribute to research for medical conditions that matter most to them, regardless of their location or ability to travel.

Accepts healthy volunteers
  • 26 Jan, 2022
  • 1 location