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Found 1314 clinical trials
Featured trial
Valacyclovir for Mild Cognitive Impairment (VALMCI)

mild cognitive impairment (MCI) patients (eMCI and lMCI). The trial will directly address the long-standing viral etiology hypothesis of Alzheimer's disease (AD) which posits that viruses, particularly

  • 47 views
  • 08 Sep, 2022
  • 1 location
Featured trial
Cognitive Fitness for Depression in Older Adults

This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance …

  • 85 views
  • 22 Jan, 2022
  • 1 location
Featured trial
Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Biotics_RTT) (Biotics_RTT)

The study will examine the potential efficacy and safety of two pre- and post-biotics on markers for gut inflammation and intestinal microbiota ecology in patients with Rett syndrome. Moreover, this trial will search for possible effects on epileptogenesis and quality of life.

seizure
  • 2 views
  • 11 Jul, 2022
  • 1 location
Featured trial
AGITATION ASSOCIATED WITH DEMENTIA OF THE ALZHEIMER’S TYPE

A PERSON WITH ALZHEIMER'S MAY FEEL ANXIOUS OR AGITATED. HE OR SHE MAY BECOME RESTLESS, CAUSING A NEED TO MOVE AROUND OR PACE, OR BECOME UPSET IN CERTAIN PLACES.  

  • 29 views
  • 08 Dec, 2020
  • 1 location
Featured trial
GAIN: GingipAIN Inhibitor for Treatment of Alzheimer's Disease

GAIN is a clinical trial evaluating whether an investigational drug is safe and can stop the progression of Alzheimer’s Disease by reducing bacterial damage in the brain. The P

senile plaques
  • 153 views
  • 08 Dec, 2020
  • 1 location
Featured trial
NICE-AD (Neurostimulation for Cognitive Enhancement in Alzheimer’s Disease)

The NICE-AD study is a home-based clinical trial examining a treatment for Alzheimer’s Disease. We are interested in examining the effects of the device on cognition, mood, and neuroplasticity

dementia
  • 32 views
  • 02 Nov, 2021
  • 1 location
Featured trial
Vielight Neuro RX Gamma Photobiomodulation Device for Moderate to Severe Alzheimer's Disease

quality of life in patients with moderate to severe Alzheimer's Disease. Treatment will occur at home-based treatment sessions with the device.A potential participant will undergo

mental state examination
stroke
mini-mental state examination
  • 70 views
  • 30 Jul, 2021
  • 9 locations
Featured trial
Cognitive Trial – A Phase III Safety and Efficacy Study of ALZT-OP1 in Individuals with Evidence of Early Alzheimer’s Disease

Cognitive Trial – A Phase III Safety and Efficacy Study of ALZT-OP1 in Individuals with Evidence of Early Alzheimer’s Disease

memantine
memory impairment
acetylcholinesterase
acetylcholinesterase inhibitor
demented
  • 881 views
  • 23 Nov, 2020
  • 3 locations
Featured trial
A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, PARALLEL-GROUP, 52-WEEK STUDY EVALUATING THE SAFETY AND EFFICACY OF SIMUFILAM 100 MG TABLETS IN SUBJECTS WITH MILD TO MODERATE ALZHEIMER’S DISEASE

Simufilam is an experimental treatment, meaning that it has not yet been approved by the United States (US) Food and Drug Administration (FDA). In this study, the study medicine will be compared to a placebo. A placebo is a pill that looks exactly like the study medicine but does not …

  • 2 views
  • 25 Mar, 2022
  • 1 location
Featured trial
BRAIN-SILK SIMS.

This study is looking for people who are over 75, are in hospice care, and have Alzheimer’s (or normal cognition, for a comparison). The study is developing a new brain scan for Alzheimer’s.

  • 0 views
  • 15 Sep, 2020
  • 1 location