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Found 17 clinical trials
Personalized tDCS in Elderly Fallers Study

The objective of this study is to determine if a four-week, 20-session intervention of personalized transcranial direct current stimulation (tDCS), as compared to sham intervention, improves dual task standing and walking performance (Aim 1), as well as other physical (Aim 2) and cognitive (Aim 3) factors on the causal pathway …

  • 13 views
  • 14 Feb, 2022
  • 1 location
Border Region Area Lifestyle Intervention Study for Healthy Neurocognitive Ageing Diabetes

The objective is to evaluate a culturally tailored adaptation of The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) protocol targeted for individuals with Type 2 diabetes mellitus (DM) living in the border areas of Ireland. The primary research question to be addressed is; what is the …

  • 0 views
  • 07 Apr, 2022
  • 1 location
Trial-Ready Cohort-Down Syndrome (TRC-DS) (TRC-DS)

The purpose of the Trial-Ready Cohort - Down Syndrome (TRC-DS) is to enroll 120 non-demented adults (ages 35-55) with Down syndrome (DS) into a trial ready cohort (TRC). Participants enrolled in

demented
cognitive assessment
dementia
alzheimer's disease
  • 12 views
  • 26 May, 2022
  • 8 locations
The Sleep Amyloid, Slow WAve Race and Ethnicity Study (Sleep AWARE)

recent community based study of non-demented elderly, black race was associated with higher amyloid burden after adjusting for vascular risk factors, suggesting the presence of additional physiological

amyloid
demented
polysomnography
amyloidosis
Accepts healthy volunteers
  • 0 views
  • 24 Jan, 2022
  • 1 location
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly

them up for at least 3 years. Eligible people are non-demented adults with subjective cognitive complaint, which are reported either by the participant, the proxy or both. Participants are identified

demented
cognitive assessment
mild cognitive impairment
dementia
cognitive impairment
  • 3 views
  • 26 Feb, 2022
  • 1 location
Visualising Cerebral and Peripheral Cholinergic Nerves in Patients With Dementia Lewy Bodies.

Lewy Body Dementia (DLB) is the second most common type of neurodegenerative dementia and characterized by loss of cholinergic neurons in the cerebrum and possibly also internal organs. A novel tracer, 18F-fluoroethoxybenzovesamicol (18F-FEOBV), binds to the cholinergic vesicle transporter, a protein expressed uniquely in the vesicles of cholinergic pre-synapses. Our …

PET-CT
dopamine
Accepts healthy volunteers
cognitive assessment
dementia
  • 0 views
  • 03 Jun, 2022
  • 1 location
Longitudinal Study of Mild Cognitive Impairment in Parkinson's Disease (PD-MCI)

Parkinson's disease (PD) is known for its motor symptoms and affects more than 100,000 Canadians. However, PD patients also show cognitive deficits and neuropsychiatric problems that significantly impair their quality of life. The occurrence of dementia in PD is much higher than in the general population. The proposed study will …

motor symptoms
demented
dementia
cognitive disorder
cognitive impairment
  • 125 views
  • 23 Feb, 2022
  • 1 location