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Found 18 clinical trials
Study on Early Brain Injury Mechanism and Comprehensive Intervention of VCI

project is to establish a study cohort of non-demented vascular cognitive impairment(VCIND). Neurocognitive function assessment combined with multimodal MRI including ASL, DCE, DTI and BOLD techniques

  • 21 views
  • 19 Aug, 2021
  • 1 location
Test-retest Study With [18F]PI-2620 in PSP-RS and NDC

The overall goal of this protocol is to evaluate the imaging characteristics of [18F]PI-2620 using positron emission tomography (PET) in patients with progressive supranuclear palsy, Richardson's syndrome (PSP-RS)

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 1 location
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

neurodegenerative disorder
Accepts healthy volunteers
cancer
screening procedures
neurodegenerative diseases
  • 176 views
  • 25 Feb, 2022
  • 1 location
The Effects of Chicken Extract and a Peptide Supplement for the Prevention of Cognitive Decline in Non-demented Elderly Adults

-demented elderly adults using a three-arm, randomized, placebo-controlled clinical trial design.

Accepts healthy volunteers
  • 0 views
  • 25 Jan, 2022
  • 3 locations
Effects of Brain Beta-Amyloid on Postoperative Cognition

presence of brain beta-amyloid plaques in non-demented subjects increases postoperative cognitive decline (POCD) in elderly subjects scheduled for hip or knee replacement. The investigators

cognitive decline
dementia
18f-av-45
  • 0 views
  • 30 Jan, 2022
  • 1 location
Multidisciplinary Home-based Tele-rehabilitation Intervention (TeleFall)

national, single-center, single-blind, randomized, case-control study, non-demented patients with idiopathic PD with high risk of falling will be included. The main objective of this study is to determine

demented
  • 0 views
  • 25 Jan, 2022
  • 1 location
tDCS on Parkinson's Disease Cognition (tDCS-PD-fMRI)

relatively slowly progressing cognitive deficits (compared to their motor deficits) have become one of the major challenges. Approximately 80% of PD patients eventually become demented. Therefore cognitive

antipsychotics
cognitive disorder
brain stimulation
demented
cholinesterase
  • 165 views
  • 20 Apr, 2022
  • 1 location
Lithium As a Treatment to Prevent Impairment of Cognition in Elders (LATTICE)

broadly in the general population. This study will examine whether lithium has anti-dementia properties in older adults who have mild cognitive impairment and are at risk of becoming demented.

demented
memory loss
dementia
alzheimer's disease
  • 0 views
  • 25 Jan, 2022
  • 1 location
MRI and PET Biomarkers for Cognitive Decline in Older Adults

The purpose of this research study is to understand the factors that underlie changes in thinking and memory with increasing age. The investigators will test the usefulness of MRI, PET, and cognitive testing in detecting subtle changes in the brain that precede cognitive decline. An addendum to this study includes …

mini-mental state examination
mental state examination
Accepts healthy volunteers
positron emission tomography
dementia
  • 0 views
  • 24 Jan, 2022
  • 1 location
Coaching for Cognition in Alzheimer's (COCOA)

One major study objective is, using 2 study arms (data-driven health coaching plus RC vs. RC only), to evaluate the efficacy of data-driven health coaching. 'RC only' will serve as the control group. Participants will be enrolled in the trial on the basis of an existence of objective cognitive impairment …

cognitive impairment
cognitive assessment
dementia
mild cognitive impairment
cognitive training
  • 33 views
  • 26 Feb, 2022
  • 1 location