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Found 247 clinical trials
Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery

Delirium is common in the elderly after hip fracture surgery, and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after hip fracture surgery

  • 0 views
  • 08 Dec, 2021
  • 1 location
Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery

Sleep disorder and delirium are common problems in intensive care unit (ICU) patients, and may lead to poor prognosis. The investigators' previous study showed that nighttime infusion of low

dexmedetomidine
delirium
  • 0 views
  • 23 Sep, 2021
  • 1 location
Melatonin for Prevention of Postoperative Delirium After Lower Limb Fracture Surgery in Elderly Patients (DELIRLESS)

Postoperative delirium (POD) is one of the most frequent complications after surgery in elderly patients, affecting between 20 and 40% of patients older than 60 after major surgery. This

  • 0 views
  • 15 Jul, 2022
  • 1 location
Study on Opioid-free Anesthesia Protocol With S-ketamine and Propofol

explore the effects of S-ketamine on postoperative awakening time and extubation time, nausea and vomiting, hypoxemia, and delirium.

  • 0 views
  • 04 Oct, 2022
  • 1 location
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients (CODEX)

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

heart surgery
dexmedetomidine
thoracotomy
cognitive deficits
coronary artery bypass graft
  • 10 views
  • 28 Feb, 2022
  • 1 location
Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery

and inflammatory response, improving analgesic efficacy and sleep quality, and reducing delirium incidence.

cancer surgery
dexmedetomidine
morphine
analgesia
metastasis
  • 8 views
  • 30 Apr, 2022
  • 1 location
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children (PICU Up!)

occupational therapist within 3 days of PICU admission. Given the interplay of sedation, delirium, sleep, and immobility in the PICU, single-component interventions, such as sedation protocolization, have not

  • 0 views
  • 07 Oct, 2022
  • 9 locations
Testing the Efficacy of FFC-AC-EIT in Patients With Alzheimer's Disease and Related Dementias

, delirium, falls, behavioral symptoms associated with dementia (BPSD) and longer lengths of stay. Physical activity during hospitalization (e.g., mobility,bathing, dressing) has a positive impact on older

BPSD
cognitive assessment
dementia
alzheimer's disease
behavioral symptoms
  • 3 views
  • 28 Oct, 2022
  • 4 locations
HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 (HIP ATTACK-2) Trial (HIP ATTACK-2)

congestive heart failure, and stroke), delirium, length of stay, pain, and quality of life.

  • 0 views
  • 23 Oct, 2022
  • 25 locations
Alpha 2 Agonists for Sedation to Produce Better Outcomes From Critical Illness (A2B Trial): A Randomised, Parallel-group, Allocation Concealed, Controlled, Open, Phase 3 Pragmatic Clinical and Cost- Effectiveness Trial With Internal Pilot (A2B)

sedated can make their ICU stay longer, can cause ICU confusion (delirium) and afterwards may cause distressing memories. Ideally patients should be kept less sedated, but it is difficult to get the

  • 327 views
  • 23 Oct, 2022
  • 28 locations