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Found 49 clinical trials
Transforaminal Lumbar Interbody Fusion (TLIF) (TLIF)

This is a global, multi-center, prospective, randomized, blinded, controlled pivotal study. Clinical and radiological evaluation will be performed preoperatively and postoperatively up to 24 months; and endpoint success will be determined at 24 months postoperatively. Overall a maximum of 1017 subjects will be enrolled and treated. The purpose of the …

  • 366 views
  • 11 Aug, 2022
  • 33 locations
Evaluation of Proprioception (PROPRIO_TPG)

The osteoarthritis (OA) is a chronic and degenerative disease which brings articular cartilage degeneration. As a consequence, balance and proprioception could be dangerously reduced after total

  • 0 views
  • 19 Feb, 2022
  • 1 location
Sensory Integration Therapy Training in Patients With Lumbar Spinal Stenosis

Lumbar spinal stenosis is a common degenerative disease in the elderly. Patients are often accompanied by paresthesias and decreased musculoskeletal system functions, resulting in disability and

Accepts healthy volunteers
  • 0 views
  • 09 Jul, 2022
  • 1 location
Norwegian Distal Ulna Resection - Replacement Study (NORDURR)

Osteoarthritis of the joint between the forearm bones at the wrist (distal radioulnar joint, DRUJ) is a common sequel of fracture and ligament injuries or degenerative disease of the wrist

  • 0 views
  • 11 May, 2022
  • 2 locations
Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis

Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment

local anesthetics
ct scan
anesthesia
local anesthesia
spinal decompression
  • 10 views
  • 26 Feb, 2022
  • 1 location
OCTA in Mild Cognitive Impairment and Alzheimer's Disease

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography angiography (OCTA) to assess the structure and function of the retinal microvasculature in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD) or other neurodegenerative disease, multiple sclerosis, and Huntington's disease.

multiple sclerosis
mild cognitive impairment
alzheimer's disease
parkinson's disease
chorea
  • 31 views
  • 25 Jan, 2022
  • 1 location
3T MRI in Patients With Deep Brain Stimulation (DBS)

Deep brain stimulation (DBS) is an established treatment for advanced Parkinson's disease, medically refractory tremor, dystonia and obsessive compulsive disorder. Several hypotheses driven DBS trials are underway to study modulation of circuit dysfunction in other neurological and psychiatric disorders like epilepsy, Alzheimer's disease and depression. Recent reports suggest profound effects …

  • 30 views
  • 22 Mar, 2022
  • 1 location
Tocotrienols in Parkinson's Disease (PD)

A study using Parkinson's disease animal model, transgenic fruit flies, demonstrated the potential of using tocotrienols (HOV-12020) as a therapeutic agent for delaying Parkinsonian motor dysfunctions. The proposed study aims to enrol 100 PD patients in a randomized placebo-controlled trial to investigate the effects of tocotrienols (HOV-12020) in motor and …

dopamine agonists
tremor
resting tremor
levodopa
parkinsonism
  • 3 views
  • 25 Jan, 2022
  • 2 locations
Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD (FUSE)

with anterior cervical discectomy and fusion (ACDF) in the treatment of multi-level cervical degenerative disease.

analgesics
conservative management
cervical arthrodesis
degenerative disease
discectomy
  • 60 views
  • 01 May, 2022
  • 17 locations
The Confounding Burden of Psychological Impairments in Cervical Spine Surgery

indicated for surgery for cervical degenerative disease (CDD) will be screened for yellow flags using validated tools to assess pain. Cognitive-behavioral therapy (CBT) will be used to modify yellow flags

  • 7 views
  • 19 Apr, 2022
  • 1 location