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Found 5 clinical trials
Deflazacort vs. Prednisolone in Acute-stage ABPA

. Unfortunately, numerous toxicities and adverse effects have been attributed to glucocorticoids related to both the average dose and cumulative duration of use. Deflazacort is a oxazoline steroid with

  • 28 Feb, 2021
  • 1 location
Study of the Excretion of Orally Administered Corticosteroids for the Improval of the Detection of Said Substances in Anti-doping Controls

>Objectives To conduct excretion studies with dexamethasone, methylprednisolone and deflazacort in order to define notification levels and wash-out periods after the administration of a

  • 07 Apr, 2021
  • 1 location
A Phase 3 Trial of Pamrevlumab (FG-3019) or Placebo in Combination With Systemic Corticosteroids in Ambulatory Subjects With Duchenne Muscular Dystrophy (DMD)

To evaluate the efficacy and safety of pamrevlumab versus placebo in combination with systemic corticosteroids administered every two weeks in ambulatory subjects with Duchenne muscular dystrophy (age 6 to <12 years).

serum electrolyte
duchenne muscular dystrophy
  • 25 Jul, 2021
  • 49 locations
A Phase 3 Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy

The study will evaluate the safety and efficacy of gene therapy in boys with DMD. It is a randomized, double-blind, placebo-controlled study with two thirds of participants assigned to gene therapy. The one third of participants who are randomized to the placebo arm will have an opportunity for treatment with …

duchenne muscular dystrophy
gene therapy
  • 22 Jul, 2021
  • 26 locations
Focal Laser Ablation for the Treatment of Focal Low-Intermediate Risk Prostate Cancer

Short-term Efficacy of Transperineal Laser Ablation (TPLA) with Image Fusion and Multi-parametric (mpMRI) Follow-up in Focal Low-intermediate Risk Prostate Cancer. It is an interventional pilot study. The clinical evaluation will be carried out at different times as follows Time 0: recruitment and eligibility assessment (patient selection) Time 1: interview, signing …

biopsy of prostate
multiparametric magnetic resonance imaging
  • 23 Jan, 2021
  • 1 location