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Found 1294 clinical trials
bAriatric sUrgery Registration in wOmen of Reproductive Age

The use of bariatric surgery has risen subsequently over the last decade, especially in women of reproductive age. (Unplanned) pregnancies in this subgroup are not rare because of e.g. an increased fertility (because of the weight loss) and a possible ineffectiveness of contraceptives (because of a malabsorption in the intestine). …

high risk pregnancy
  • 15 May, 2021
  • 1 location
Diadenosine Polyphosphates and Mucin Associated With Ocular Surface Disorders

Dry eye disease, ocular graft-versus-host disease (GVHD), and superior limbic keratoconjunctivitis (SLK) are all ocular surface disorders which mostly involve the outer surface of the eye. Many of the ocular surface disorders may result from or be aggravated by the mechanical stress from eyelid blinking. Specifically, SLK is an inflammatory …

eye disease
contact lens prescription
graft versus host disease
immunosuppressive agents
  • 22 Jan, 2021
  • 1 location
Patient Reported Outcomes Measures to Predict Pancreatic Surgery Outcomes (PRO-PANC1)

This is a prospective single-center observational study with the mail objective to identify specific subgroups of patients planned for pancreatic resection, at high risk for postoperative morbidity and impaired recovery through preoperative screening of physical, functional, nutritional and psychological risk factors using patient reported questionnaires and performance tests. Consecutive patients …

pancreatic resection
pancreatic surgery
  • 14 Apr, 2022
  • 1 location
Cohort Study of Airway Microecology and the Pathogenesis and Evolution of Chronic Obstructive Pulmonary Disease

This study will last for 5 years (2021.2.25-2025.12.31). 210 patients (70 cases in each group) will be enrolled in this study. Eight centers in China will participate in the study. The patients will be treated with bronchoscopy alveolar lavage, and 60 ml of bronchoalveolar lavage fluid will be collected for …

  • 27 Apr, 2021
  • 1 location
Exoskeleton Footwear to Improve Walking

The purpose of this study is to determine the best assistance level of an exoskeleton footwear (EF) that can assist walking for people older than 40 with and without peripheral artery disease (PAD). The test will be performed on two different groups of people for this study that include: 1) …

intermittent claudication
peripheral arterial diseases
  • 23 Mar, 2022
  • 1 location
Evaluation of Point-of-care Ultrasound in Children From 6 Months to 15 Years With Presumptive Tuberculosis

Diagnosis of tuberculosis (TB) in children is particularly challenging in low and middle-income countries (LMIC), and a high number of children remain undiagnosed and untreated. A delay in diagnosis can lead to an increase in preventable morbidity and mortality. Point-of-care ultrasound (POCUS) is a bedside, non-invasive, inexpensive imaging tool, and …

  • 13 May, 2022
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic Inflammatory and Takotsubo Cardiomyopathy (MEMORY)

Manganese is a calcium analogue which actively enters viable cells with intact calcium-handling mechanisms and its uptake is evident by an increase in MRI-detectable T1 relaxivity of tissues. Mangafodipir is a novel manganese-based magnetic resonance imaging (MRI) contrast medium with unique biophysical properties that are ideal for application to cardiac …

Accepts healthy volunteers
heart failure
cardiac mri
  • 18 Oct, 2021
  • 1 location
PAthogen Transmission and Health Outcome Models of Enteric Disease (PATHOME)

The objective of the PATHOME study is to (1) develop statistical and computational methods for examining a complex disease system of interactions between and amongst children, animals, the environment, and enteric pathogens and (2) build a virtual laboratory for predicting which social and environmental developmental improvements best prevents multi-pathogen transmission …

  • 02 May, 2022
Post-Market Clinical Follow-up Study of A-SPINE's Products

This is a post-market clinical follow-up study that use questionnaires such as Visual Analog Scale (VAS), the Neck Disability Index (NDI), or the Oswestry Disability Index (ODI) to compare the clinical improvement effects before and after surgery.

  • 28 Apr, 2021
  • 1 location
Exploratory Observational Prospective Study in Neonatal and Pediatric Congenital Diaphragmatic Hernia

CDH is associated with lung hypoplasia, pulmonary hypertension, and left ventricular hypoplasia. Use of new STE techniques (heart ultrasound) showed that CDH newborns have decreased LV size and function, potentially explaining the non-response to iNO, and that these cardiac findings were associated with poor outcomes. Our hypothesis: CDH newborns persist …

pulmonary hypoplasia
Accepts healthy volunteers
diaphragmatic hernia
  • 27 Feb, 2022
  • 1 location