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Found 1317 clinical trials
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Alpha-1 Study: A research study for individuals with Alpha-1 Antitrypsin Deficiency

The Alpha-1 Study is a clinical research study currently enrolling individuals 18 to 78 (inclusive) with Alpha-1 Antitrypsin Deficiency.   The purpose of this study is to evaluate

alpha1-proteinase inhibitor (human)
deficiency
alpha 1-antitrypsin
  • 145 views
  • 23 Nov, 2020
  • 7 locations
featured
A Washington University research study is currently enrolling participants with primary Immune deficiency (PID). IRB ID #: 201910008

The purpose of this research study is to investigate different ways to dose with CUTAQUIG ® in patients suffering from primary Immune deficiency (PID).

immune disorder
immune disorders
primary immunodeficiency
immune deficiency
immunodeficiency
  • 0 views
  • 25 Jan, 2021
  • 1 location
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Expanded Access with Adjunctive Ganaxolone (GNX) Treatment in Children and Young Adults with Cyclin-dependent Kinase-like 5 (CDKL5) deficiency disorder (CDD)

The primary objective is to provide GNX to patients ≥ 2 years with CDD-related seizures who are refractory to, or intolerant of, standard therapy.

  • 0 views
  • 30 Jun, 2021
  • 2 locations
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Depression

deficiency of these biomolecules results in cell loss in important areas of the brain associated with motivation, emotion, perceptions, thinking, learning and memory. Reversing this deficiency with the use of

behavior therapy
transcranial magnetic stimulation
depressed mood
suicidal
treatment resistant depression
  • 0 views
  • 30 Jul, 2021
  • 1 location
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Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

>Eligibility: Adults ages 18-80 of African descent. They may have sickle cell disease or not. They must not have had a transfusion recently or have a known deficiency of pyruvate kinase

sickle cell disease
sickle cell anemia
red blood cell disorder
  • 48 views
  • 22 Dec, 2020
  • 1 location
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A Phase IV, Multicenter, Open-Label Study of the Immunogenicity of Nutropin AQ® V1.1 [Somatropin (rDNA Origin) Injection] Administered Daily to Naive Growth Hormone-Deficient Children

A Phase IV, Multicenter, Open-Label Study of the Immunogenicity of Nutropin AQ® V1.1 [Somatropin (rDNA Origin) Injection] Administered Daily to Naive Growth Hormone-Deficient Children

  • 184 views
  • 25 Mar, 2021
  • 1 location
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Role of Genetic Factors in the Pathogenesis of Lung Disease

This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes …

pulmonary disease
diabetes
pulmonary fibrosis
bronchoscopy
  • 120 views
  • 23 Nov, 2020
  • 1 location
featured
A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

  • 74 views
  • 25 Mar, 2021
  • 1 location
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Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

Background: People are living longer and are more likely to survive a heart attack if they have one. Longer life expectancy is good but it also means more people get chronic heart failure over time. This is a condition in which the heart doesn't pump blood as well as it …

cardiopulmonary exercise testing
systolic heart failure
chronic heart failure
radionuclide ventriculography
heart failure
  • 77 views
  • 09 Apr, 2019
  • 1 location
featured
Do You Have Osteoporosis?

Do You Have Osteoporosis?

  • 1122 views
  • 25 Mar, 2021
  • 1 location