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Found 34 clinical trials
Rivaroxaban for the Treatment of Symptomatic Isolated Distal Deep Vein Thrombosis

The treatment of isolated distal deep vein thrombosis remains one of the most debated issues in the field of venous thromboembolism and only very few studies have directly addressed the issue of treatment in objectively confirmed isolated distal deep vein thrombosis. Aim of this study is to assess the long-term …

fondaparinux
heparin
deep venous thrombosis of lower extremity
deep vein thrombosis
rivaroxaban
  • 23 views
  • 22 Jan, 2021
  • 7 locations
Phase 1 Pediatric Pharmacokinetics/Pharmacodynamics (PK/PD) Study

This is the first evaluation of edoxaban in pediatric subjects. In this Phase 1 study, a single dose of edoxaban will be given to pediatric subjects who require anticoagulant therapy to see what the body does to the drug (pharmacokinetics) and what the drug does to the body (pharmacodynamics), and …

aspirin
anticoagulant therapy
edoxaban
anticoagulants
  • 196 views
  • 05 May, 2021
  • 40 locations
A Performance Evaluation of the LumiraDx Point Of Care D-dimer Assay

In patients with symptoms of Venous Thromboembolism (VTE) (mainly deep vein thrombosis (DVT) or pulmonary embolism (PE)), the study will evaluate the agreement between the D-Dimer measurements from the LumiraDx POC D-Dimer assay and a reference method, as an aid in diagnosis, assessment and exclusion of DVT and PE.

  • 0 views
  • 26 Mar, 2021
  • 11 locations
Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with confirmed VTE. This study is designed to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of edoxaban and to compare the efficacy and safety of edoxaban against standard of care in …

heparin
vitamin k antagonist
edoxaban
heparin therapy
probe
  • 0 views
  • 28 Jan, 2021
  • 170 locations
Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events

The study will evaluate the effectiveness of a novel, real-time risk prediction model for identifying pediatric patients at risk for developing in-hospital blood clots (or venous thromboembolism [VTE]) based on data easily extracted from the electronic medical record. The study will assess whether using the risk percentages for developing VTE …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)

The risk of developing a blood clot occurs in up to 60% of all critical care patients. Many times enoxaparin (or Lovenox) is given to patients who are at a higher risk of developing clots in their legs or lungs. There are two standard doses of enoxaparin that are recommended …

enoxaparin
blood clot
critical illness
clot
lovenox
  • 10 views
  • 18 Mar, 2021
  • 1 location
Point-of-care Ultrasound in Finland

This study has two aims. Deep venous thrombosis (DVT) is a common suspected medical condition. If it cannot be excluded clinically and using D-dimer, ultrasound examination is required. An option for traditional radiologist-performed ultrasound is a 2-point compression ultrasound (2-CUS). The safety of this technique is proven. However there does …

pneumothorax
d-dimer
ultrasound examination
dvts
deep vein thrombosis
  • 19 views
  • 22 Jan, 2021
  • 4 locations
Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19

Worldwide observational studies indicate a significant prothrombogenic effect associated with SARS-CoV-2 infection with a high incidence of venous thromboembolism (VTE), notably life-threatening pulmonary embolism. According to recommendations for acute medical illnesses, all COVID-19 hospitalized patients should be given VTE prophylaxis such as a low molecular weight heparin (LMWH). A standard …

enoxaparin
heparin
covid-19
pneumonia
PCR test
  • 7 views
  • 27 Jan, 2021
  • 18 locations
Improving Safety of Diagnosis and Therapy in the Inpatient Setting

To improve the safety of diagnosis and therapy for a set of conditions and undifferentiated symptoms for hospitalized patients, the investigators will employ a set of methods and tools from the disciplines of systems engineering, human factors, quality improvement,and data analytics to thoroughly analyze the problem, design and develop potential …

chest pain
clot
undernutrition
soft tissue infection
cellulitis
  • 87 views
  • 25 Jan, 2021
  • 1 location
Deep Vein Thrombosis Prophylaxis Adherence: Enoxaparin vs Rivaroxaban

The objective of this study is to compare oral rivaroxaban with injectable enoxaparin in orthopaedic trauma patients to determine if orally administered rivaroxaban once daily carries greater compliance and overall satisfaction than enoxaparin self-administered by subcutaneous injection once daily.

enoxaparin
thromboembolism prophylaxis
deep venous thrombosis of lower extremity
deep vein thrombosis
thrombosis
  • 5 views
  • 23 Jan, 2021
  • 1 location