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Found 42 clinical trials
BIOTRONIK- A Prospective, Randomised, Multi-center Study to Assess the Safety of the Orsiro Mission Stent Compared to Resolute Onyx Stent in Subjects at High Risk of Bleeding in Combination With 1-month Dual Antiplatelet Therapy (DAPT) (BIOFLOW-DAPT)

BIOFLOW-DAPT is a prospective, multi-center, international, two-arm randomised controlled clinical study. A total of 1,948 subjects will be randomised 1:1 to receive either Orsiro or Resolute

  • 0 views
  • 16 Oct, 2022
  • 1 location
SAPT Versus DAPT in Incomplete Revascularization After CABG

The study aims to compare the efficacy of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) in patients with incomplete revascularization after coronary artery bypass

revascularisation
bypass graft
dapt
aspirin
ticagrelor
  • 0 views
  • 04 Oct, 2022
  • 1 location
1-month vs 12-month DAPT for ACS Patients Who Underwent PCI Stratified by IVUS: IVUS-ACS and ULTIMATE-DAPT Trials

Prospective, multicenter, randomized, double-blind, placebo-controlled trials.

angina pectoris
percutaneous coronary intervention
dapt
ticagrelor
angiography
  • 0 views
  • 18 Nov, 2021
  • 1 location
Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD)

This study is a prospective, multicenter, parallel, open-label, randomized, controlled, superiority trial. It is planned to recruit 8,250 patients with multi-vessel disease(MVD), and the patients will be followed-up for 12 months after being implanted with a drug-eluting stent (DES) at one of 100 different centers. All patients will be randomly …

dapt
clopidogrel
aspirin
antiplatelet therapy
  • 0 views
  • 04 Oct, 2022
  • 95 locations
Clopidogrel Versus Aspirin MOnotherapy After 1- to 3-month of Dual-antiplatelet thErapy Following Zotarolimus-eluting Onyx Stents Implantation; C-MODE Trial

Previous randomized clinical trials have deomonstrated the efficacy and safety of short-term dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI), however, the single

  • 0 views
  • 22 Oct, 2022
  • 1 location
Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study - ARMYDA-AMULET (ARMYDA-AMULET)

The study will perform a randomized, head-to-head comparison between SAPT (aspirin) and DAPT (aspirin plus clopidogrel) after percutaneous LAA closure with implantation of the Amulet device

  • 0 views
  • 21 Oct, 2022
  • 6 locations
COMPARE STEMI ONE- Comparison Of Reduced DAPT Followed by P2Y12 Inhibitor Monotherapy With Prasugrel vs stAndard Regimen in STEMI Patients Treated With OCT-guided vs aNgio-guided completE Revascularization

The study is a multi-centre, Open-label, Randomized Controlled, 1:1 trial comparing Prasugrel-based short DAPT (30-45 days) followed by Prasugrel monotherapy versus standard DAPT regimen in

clot
stemi
dapt
prasugrel
revascularisation
  • 0 views
  • 10 Oct, 2022
  • 2 locations
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial (HOST-IDEA)

(DAPT) for these stent systems still needs to be established. With a 2x2 factorial design for patients of stable angina or silent ischemia, the investigators formulate a head-to-head randomized

cardiac death
biodegradable polymer
angina pectoris
dapt
sirolimus
  • 0 views
  • 26 Jan, 2022
  • 4 locations
CHoice of Optimal Anti-Thrombotic Strategy in Patients Undergoing Implantation of Coronary Drug-Eluting Stents 4 (SMART-CHOICE4)

(BioFreedom Ultra) with biodegradable polymer ultrathin sirolimus-eluting stents (Orsiro Mission) and prasugrel monotherapy after 1-month dual antiplatelet therapy (DAPT) of aspirin plus prasugrel with 12

biodegradable polymer
percutaneous coronary intervention
dapt
prasugrel
sirolimus
  • 0 views
  • 25 May, 2022
  • 1 location
Direct Oral Anticoagulants for Prevention of lEft ventRIcular Thrombus After Anterior Acute Myocardial InFarction - APERITIF

(NCT04050956). Among them, eligible Patients for "APERITIF" will be randomized into two groups: Dual Anti-Platelet Therapy (DAPT) alone or DAPT plus rivaroxaban 2.5mg twice daily for 4 weeks, prescribed as

  • 1 views
  • 03 Nov, 2021
  • 1 location