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Found 10 clinical trials
Nerivio Device for Treatment of New Daily Headache Persistence (NDHP)

The goal of this study is to examine the effects of the Remote Electrical Neuromodulation (REN) device on adolescents ages 12-17 who have been diagnosed with New Daily Persistent Headache (NDPH). Pediatric patients with a diagnosis of new daily persistent headache are typically resistant to standard pharmacologic treatments and often …

  • 0 views
  • 26 Apr, 2022
  • 1 location
Safety and Efficacy of Non-invasive Vagus Nerve Stimulation in the Treatment of Headache in Subarachnoid Hemorrhage (VANQUISH)

This is a single site, randomized, sham-controlled, double blinded pilot study assessing the feasibility, safety, tolerability, and efficacy of non-invasive VNS (nVNS), gammaCore, in the treatment of headache in subarachnoid hemorrhage (SAH). 40 participants will be enrolled, 20 in the active device arm and 20 in the sham arm. The …

  • 0 views
  • 24 Feb, 2022
  • 1 location
Mind and Body Approaches to Pain Reduction in Youth With Migraine

study design of this mechanistic investigation includes functional magnetic resonance imaging (fMRI), daily headache diaries, assessment of conditioned pain modulation via quantitative sensory testing

cognitive therapy
behavioral therapy
amitriptyline
headache
daily headache
  • 19 views
  • 24 Mar, 2022
  • 1 location
Sphenopalatine Block Versus Greater Occipital Nerve Block in PDPH

etiologies like migraine , cluster headache and chronic daily headache with encouraging results. Greater Occipital Nerve (GON) arises from C2-3 segments, its most proximal part lies between obliqua capitis

  • 0 views
  • 25 Mar, 2022
  • 1 location
Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia

This study is a randomized controlled trial, assessing the effect of a single platelet rich plasma (PRP) injection in post traumatic (concussive) greater occipital neuralgia. This study will compare the effects of a single PRP injection to injection with steroid and anesthetic. There will also be a third arm to …

neuralgia
lidocaine
occipital neuralgia
Accepts healthy volunteers
headache
  • 7 views
  • 09 Oct, 2021
  • 1 location
Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

The purpose of this study is to determine if prazosin is more effective than placebo in decreasing frequency, severity, disability, and other negative effects of headaches related to mild traumatic brain injury in Service Members and Veterans.

disoriented
headache
confusion
post-traumatic stress disorder
coma
  • 59 views
  • 23 Feb, 2022
  • 1 location
Oral Contraceptive Pill Compared With Vitamin E in Women With Migraine (WHATT)

Open-label randomized controlled trial to study the efficacy of continuous daily use of ethinylestradiol/levonorgestrel (30/150 µg/day) compared with vitamin E (400 IU/day) in the treatment of women with menstrually-related and perimenopausal migraine.

menstrual migraine
  • 3 views
  • 27 Apr, 2022
  • 1 location
Analysis of Headache Chronification With Imaging Deep Phenotyping and Proteomics

Study is aimed at determining why some patients with episodic headache proceed to chronic daily or near daily headaches. The Investigators seek to discover differences in brain anatomy and

daily headaches
headache
blood products
  • 37 views
  • 29 Sep, 2021
  • 1 location
Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches Headaches

This novel pilot project will assess the effectiveness of corticosteroids in treatment of acute post-concussion headache. The investigators hypothesize that the use of corticosteroids will cause significant headache reduction in frequency and/or intensity than individuals who undergo the current standard of care. Additionally, the investigators hypothesize that corticosteroid use will …

headache
  • 0 views
  • 16 Nov, 2021
  • 1 location
CandeSpartan Study. Candesartan Spanish Response-prediction and Tolerability Study (CandeSpartan)

Observational, prospective, descriptive, open study on response predictors and tolerability of Candesartan in patients >18 years with episodic or chronic migraine with prior failure of three or more preventive drugs. Patients will receive Candesartan the same manner and intensity if they were not enrolled in the study. Vital signs, clinical …

chronic migraine
migraine
headache
headache occurring
headache disorder
  • 2 views
  • 26 Mar, 2022
  • 1 location