Found 9 clinical trials
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more …
- 103 views
- 07 Nov, 2020
- 9 locations
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery. Giving more chemotherapy after surgery may kill any remaining tumor cells. It is not …
- 9 views
- 07 Nov, 2020
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation Radiation Therapy and/or Surgery in Treating Patients With Ewing's Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. It is …
- 410 views
- 07 Nov, 2020
- 4 locations
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
Vincristine Dactinomycin and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma
RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by
- 53 views
- 07 Nov, 2020
- 2 locations
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
Vincristine Dactinomycin and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal Rhabdomyosarcoma
RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by
- 36 views
- 07 Nov, 2020
- 22 locations
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
This randomized phase III trial studies how well combination chemotherapy (vincristine sulfate, dactinomycin, cyclophosphamide alternated with vincristine sulfate and irinotecan hydrochloride or
- 292 views
- 11 Apr, 2021
- 287 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Musculoskeletal
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Currently Recruiting
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm
- 0 views
- 05 Feb, 2021
- 7 locations
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Multi-country trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An observational study
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For all genders
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Currently Recruiting
Pharmacokinetics of Dactinomycin in Young Patients With Cancer
RATIONALE: Studying samples of blood in the laboratory from patients with cancer receiving dactinomycin may help doctors learn how dactinomycin works in the body and how patients will
- 15 views
- 07 Nov, 2020
- 8 locations
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Accepting pediatric ages
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Accepting Seniors
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10s of participants
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An observational study
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For all genders
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Currently Recruiting
Description of Eosinophilic Pneumonia in BJI/PJI Treated by Daptomycin
Daptomycin is an antibiotic from the family of cyclic lipopeptides, bactericide, concentration-dependent. Its spectrum concerns Gram-positive bacteria. Since the authorization of daptomycin in 2006, cases of eosinophilic pneumonia and pulmonary eosinophilia associated with its use have been reported in Europe and worldwide. The purpose of this study is to describe …
- 0 views
- 26 Jan, 2021
- 1 location