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Found 3 clinical trials
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm

undifferentiated pleomorphic sarcoma
systemic therapy
cancer chemotherapy
alveolar soft part sarcoma
platelet count
  • 03 Mar, 2022
  • 7 locations
Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas (REGOSTA)

This is a randomized, double-blinded, 2 arms study concerning patients with bone sarcoma after the first line therapy. In the first arm, patients will be treated with regorafenib for a maximum of 12 months as maintenance therapy after first line therapy, whereas in the second arm, patients will be treated …

ewing's sarcoma
cancer chemotherapy
Accepts healthy volunteers
  • 23 May, 2022
  • 4 locations
Pharmacokinetics and Toxicodynamics of Daptomycin in Bone and Joint Infections (PKTOXDAP)

the aim of this study is to investigate the relationship between exposure to daptomycin and the occurrence of muscle toxicity or eosinophilic pneumonia in patients treated with daptomycin for bone and joint infection

  • 16 May, 2022
  • 1 location