cytotoxic chemotherapy Clinical Research Trials

Study of Capmatinib Efficacy in Comparison With Docetaxel in Previously Treated Participants With Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation

, stopping cancer cells from growing. Docetaxel is a standard chemotherapy medicine commonly used to treat your type of lung cancer. This standard, anti-cancer medicine is a cytotoxic chemotherapy.

cancer chemotherapy

lung carcinoma

systemic therapy

epidermal growth factor

docetaxel

0 views
03 Apr, 2021
40 locations

BEAT-meso: Bevacizumab and Atezolizumab in Malignant Pleural Mesothelioma

The aim of this clinical trial is to assess the effect of treatment with a monoclonal antibody called atezolizumab in patients diagnosed with a type of lung cancer called malignant pleural mesothelioma. The efficacy (whether the treatment works), safety and tolerability (side effects of treatment) of atezolizumab plus bevacizumab in …

57 views
22 Feb, 2021
54 locations

A Randomized Study Comparing Lamivudine Versus Adefovir Dipivoxil for Prevention of zHBV Reactivation in HBsAg Seropositive Patients Undergoing Cytotoxic Chemotherapy

Liver diseases due to hepatitis B reactivation are serious causes of morbidity and mortality in hepatitis B infected patients treated with chemotherapy. We have previously shown that with pre-emptive use of lamivudine, one can drastically reduce liver-related morbidity and mortality in such patients. However, due to the development of hepatitis …

adefovir

liver disease

hepatitis b antigen

hepatitis

lamivudine

8 views
07 Nov, 2020
1 location

The Role of Ruxolitinib in Secondary Acute Myelogenous Leukemia Evolving From Myeloproliferative Neoplasm

This trial aimed to investigate the therapeutic efficacy of ruxolitinib in combination with cytotoxic chemotherapy for post-myeloproliferative neoplasm secondary acute myeloid leukemia.

1 views
24 Jan, 2021
2 locations

Acalabrutinib With Rituximab and Lenalidomide in Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

NCCN guidelines for B cell lymphoma suggest that patients with relapsed/refractory aggressive NHL who are candidate for high-dose therapy should receive combination of cytotoxic chemotherapies

0 views
23 Jan, 2021
1 location

A Clinical Trial to Evaluate AZD7648 Alone and in Combination With Other Anti-cancer Agents in Patients With Advanced Cancers.

This is a modular Phase I/IIa, open-label, multi-centre, study of AZD7648 administered orally, either as a monotherapy, or in combination with either cytotoxic chemotherapies or novel anti

antineoplastic

oophorectomy

12 views
27 Apr, 2021
4 locations

LEAn Body Mass Normalization of OXaliplatin Based Chemotherapy

Cytotoxic chemotherapy is usually scaled to the body surface area (BSA), and is currently not adjusted to the body proportions of lean and fat (i.e. body composition) of individual patients

3 views
24 Jan, 2021
1 location

Sorafenib Plus Paclitaxel in Adreno-Cortical-Cancer Patients

complete surgical resection and progressing to cytotoxic chemotherapy will receive Sorafenib plus metronomic chemotherapy as treatment.The aim of this phase II trial is to evaluate the clinical

neutrophil count

cancer

cytotoxic chemotherapy

heparin

metastasis

67 views
07 Nov, 2020
1 location

Thalidomide and Tegafur/Uracil(UFUR) in the Treatment of Advanced Colorectal Cancer

cytotoxic chemotherapies. The first line chemotherapy containing with oxaliplatin is recommend by guideline. The use of antiangiogenic agents, either alone or in combination with other therapies

neutrophil count

liver metastasis

measurable disease

metastasis

irinotecan

7 views
07 Nov, 2020
1 location

Study of Samarium Sm-153 Lexidronam Combined With Docetaxel for Patients With Prostate Cancer

The purpose of this study is to investigate the safety, tolerability and anti-tumor effects of treatment with samarium Sm-153 lexidronam in combination with docetaxel in patients with castrate metastatic prostate cancer.

bisphosphonate

prostate cancer metastatic

adenocarcinoma

testosterone