Found 40 clinical trials
Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-Lymphocyte Antigen 4 (CTLA4) Haploinsufficiency
inflamed brain and nerve problems. Many have problems with their bone marrow causing low numbers of blood cells like platelets, red blood cells or white blood cells, which is called cytopenia. Researchers
- 2 views
- 15 Jun, 2022
- 1 location
Repurposing Metformin as a Leukemia-preventive Drug in CCUS and LR-MDS
This is a phase 2 single-arm pilot study of the efficacy and safety of metformin in patients with clonal cytopenia of undetermined significance (CCUS) or lower-risk myelodysplastic syndrome (MDS
- 0 views
- 24 Mar, 2022
- 1 location
A Study of KER-050 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes
The purpose of this study is to evaluate the effects of KER-050 on anemia in patients with very low, low or intermediate risk MDS.
- 72 views
- 05 May, 2022
- 12 locations
Exploring the Efficacy and Safety of CS20AT04 (Allogenic Bone Marrow-Derived Stem Cell) in Systemic Lupus Erythematosus Patients
of systemic lupus erythematosus patients - lupus nephritis and lupus cytopenia.
- 0 views
- 16 Apr, 2021
- 1 location
Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies (EVITA)
; i.e., clonal cytopenia of undetermined significance (CCUS), low-risk myelodysplastic syndromes (MDS), and chronic myelomonocytic leukemia (CMML)-0/1 by reversing the epigenetic changes characteristic
- 52 views
- 14 Feb, 2022
- 4 locations
TPM Regimen (Thalidomide Prednisone and Methotrexate) in LGLL
Large granular lymphocytic leukemia (LGLL) is a lymphoproliferative disease, with LGL infiltration in peripheral blood and bone marrow, hepatosplenomegaly, and cytopenia. Both T-LGLL and CLPD-NK
- 0 views
- 24 Jan, 2021
- 9 locations
Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
This clinical trial studies the use of reduced intensity chemotherapy and radiation therapy before donor stem cell transplant in treating patients with hematologic malignancies. Giving low doses of chemotherapy, such as cyclophosphamide and fludarabine phosphate, before a donor stem cell transplant may help stop the growth of cancer cells. It …
- 66 views
- 20 Apr, 2022
- 1 location
Prognostic Value of Circulating Tumoral DNA After the First 6 Months of Treatment in Patients With Waldenstr m Macroglobulinemia
disorder requires treatment only in case of symptoms, according to accurate criteria described during the second Workshop on WM i.e. in case of cytopenia, bulky organomegaly, immunological or
- 0 views
- 29 May, 2021
- 1 location
TPO-Mimetic Use in Children for Hemotopoietic Failure
This is an open label, prospective Pilot interventional study will investigate the safety and efficacy of Romiplostim, thrombopoietin (TPO) mimetic, in children (ages: 0 to 21 years) with broad scope of bone marrow failure disorders including acquired and inherited conditions as a first line of therapy along with standard of …
- 0 views
- 18 Jun, 2021
- 1 location
ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma
have the disadvantage of having a limited HSC dose leading to prolonged cytopenia and higher risk of infections. In a first in-human trial using CB expanded with the ECT-001 (UM171) molecule
- 65 views
- 15 Mar, 2022
- 1 location