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Found 747 clinical trials
Phase II Study of Toripalimab Plus Stereotactic Body Radiotherapy in Colorectal Cancer Patients With Oligometastasis

surrounding normal tissues. It is suggested that SBRT could be the most appropriate radiotherapy modality to be combined with immunotherapy since it induces the expression of a series of cytokines and new

metastasis
cytokines
solid tumour
  • 0 views
  • 23 Jan, 2021
  • 1 location
A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU)

Th17 lymphocytes reaching the eye. L-12 and IL-23 are two key cytokines involved in Th1 and Th17 polarization in uveitis, respectively. Furthermore, these two cytokines share a common subunit (p40

  • 4 views
  • 19 Feb, 2021
  • 1 location
Study of T Lymphocytes in Patients With Horton Disease

-, two key cytokines in the pathophysiology of GCA could be implicated in the pathophysiology of GCA and could constitute a predictive marker of relapse. Our hypothesis is that blood MAIT are

inflammatory disease
corticosteroids
headache
steroid therapy
corticosteroid therapy
  • 1 views
  • 23 Jan, 2021
  • 1 location
Characterization of the Immunological Profile Patients With Post-polio Syndrome

, several studies have advanced the hypothesis of immune dysregulation to this late degradation, with greater expression of pro-inflammatory cytokines, and abnormal phenotypic expression of T cells in the

  • 7 views
  • 24 Jan, 2021
  • 1 location
Lidocaine Combined With Low Opioid Anesthesia and Analgesia in Patients With Primary Liver Cancer

lidocaine concentration at the end of surgery and postoperative 24 hours, changing in liver function indicators (preoperative and postoperative 24 hours ), and the levels of natural killer cells, cytokines

  • 0 views
  • 24 Jan, 2021
  • 1 location
Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture

strength estimated by micro-FEA), muscle mass and strength, inflammatory cytokines and micro-RNAs modulating their expression. This study will provide new data concerning the importance of gut microbiota

spinal fracture
quantitative computed tomography
postmenopausal osteoporosis
bone mineral density
bone densitometry
  • 71 views
  • 23 Jan, 2021
  • 1 location
Ketogenic Diet as Protective Factor During COVID-19

intensive unit care, thus reducing pressure on health system, but also to reduce some of the pathological features of COVID-19 such as inflammation and the "cytokines storm". The ketogenic diet is a

  • 0 views
  • 26 Jan, 2021
  • 1 location
Clinical and Biological Effects of Citrus-phytochemicals in Subjective Cognitive Decline.

molecules, such as neurotransmitters, hormones and cytokines. As a result, it may be unlikely that cognitive decline may be mitigated by drugs acting on a single specific target. Plant extracts acting at

  • 0 views
  • 16 Feb, 2021
  • 1 location
Azithromycin in Post Diarrheal Haemolytic and Uremic Syndrome

death. In addition, Stx are also able to enhance the production and the release of pro inflammatory factor (IL-1, TNF, IL-6). Cytokines locally produced by Stx-stimulated cells can amplify the

  • 0 views
  • 23 Jan, 2021
  • 1 location
Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial

controlled trial to determine whether ICS by themselves or in combination with LABAs can: 1. reduce CRP levels in stable COPD patients and 2. reduce other pro-inflammatory cytokines

fluticasone
bronchodilator
corticosteroids
cigarette smoke
  • 130 views
  • 07 Nov, 2020
  • 9 locations