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Found 184 clinical trials
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Efficacy of HAD Induction With Intensified Cytarabine in Newly-diagnosed CEBPA Double Mutated Acute Myeloid Leukemia

(homoharringtonine(HHT)+cytarabine+daunorubicin) with intermediate dose cytarabine improved the survival of AML, especially in patients with CEBPA double mutation.

acute promyelocytic leukemia
acute leukemia
cytarabine
daunorubicin
hematologic malignancy
  • 0 views
  • 15 Aug, 2021
  • 1 location
None
Venetoclax Cladribine Low Dose Cytarabine and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

This phase II trial studies how well venetoclax, cladribine, low dose cytarabine, and azacitidine work in treating patients with acute myeloid leukemia that has previously not been treated

hematopoietic growth factors
tretinoin
cladribine
cytarabine
neoadjuvant therapy
  • 15 views
  • 30 May, 2021
  • 1 location
None
Fludarabine in Combination With Daunorubicin and Cytarabine Liposome in Newly-diagnosed Acute Myeloid Leukemia.

This phase 2 clinical trial will evaluate the effectiveness and safety of fludarabine in combination with CPX-351 in patients with untreated AML. Patients will receive fludarabine and CPX-351 during Induction 1 and 2 as well as 2 cycles of consolidation therapy.

  • 0 views
  • 08 Apr, 2021
  • 1 location
None
Fludarabine Cytarabine and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia

This phase Ib trial investigates the side effects and best dose of pegcrisantaspase when given together with fludarabine and cytarabine for the treatment of patients with leukemia that has come

  • 0 views
  • 06 Sep, 2021
  • 1 location
None
A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained Protocol

hematological malignancies. This finding deserves to be tested in prospective clinical trials with long-term follow-up. Cytarabine has been applied for patients with LCH but has never been evaluated in our

  • 0 views
  • 06 Mar, 2021
  • 1 location
None
Lintuzumab-Ac225 in Combination With Cladribine + Cytarabine + Filgastrim + Mitoxantrone (CLAG-M) for Relapsed/Refractory Acute Myeloid Leukemia

This is a prospective, single-center phase I clinical study aimed at determining the maximum-tolerated dose and safety of Lintuzumab-Ac225 in combination with CLAG-M chemotherapy in the management of relapsed/refractory acute myeloid leukemia. This study uses a 3+3 design to estimate the maximum-tolerated dose (MTD).

blast cells
secondary acute myeloid leukemia
cladribine
mitoxantrone
myeloproliferative disorder
  • 14 views
  • 26 May, 2021
  • 1 location
None
Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)

A prospective, single-arm, multicenter, exploratory study to evaluate the efficacy and safety of D-CLAG regimen in the treatment of relapsed or refractory acute myeloid leukemia

decitabine
blast cells
cladribine
granulocyte colony stimulating factor
cytarabine
  • 1 views
  • 26 Jan, 2021
  • 1 location
None
Milademetan Tosylate and Low-Dose Cytarabine With or Without Venetoclax in Treating Participants With Recurrent or Refractory Acute Myeloid Leukemia

This phase I/II trial studies the side effects and best dose of milademetan tosylate and to see how well it works with cytarabine with or without ventoclax in treating participants with acute

gilbert's syndrome
cytarabine
cancer
hydroxyurea
refractory acute myeloid leukemia (aml)
  • 1 views
  • 10 Nov, 2021
  • 1 location
None
Clofarabine Idarubicin Cytarabine Vincristine Sulfate and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

This phase II trial studies how well clofarabine, idarubicin, cytarabine, vincristine sulfate, and dexamethasone work in treating patients with mixed phenotype acute leukemia that is newly

clofarabine
dexamethasone
myeloid leukemia
cytarabine
cancer
  • 22 views
  • 05 Nov, 2021
  • 1 location
None
Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

This phase I/II trial studies the side effects and best dose of quizartinib when given in combination with azacitidine or cytarabine in treating patients with acute myeloid leukemia or

  • 29 views
  • 14 May, 2021
  • 1 location