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Found 161 clinical trials
Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML

The purpose of the study is to determine whether Fludarabine in combination with cytarabine is more effective than high-dose cytarabine in post-remission therapy for patients with core-binding

hydroxyurea
neoadjuvant therapy
remission
cytarabine
fludarabine
  • 41 views
  • 29 May, 2022
  • 1 location
Combination of Donafenib and Cytarabine/Daunorubicin in Relapsed AML

This phase study of Donafenib, an oral multikinase inhibitor that targets Raf kinase and receptor tyrosine kinases, is to assess safety and pharmacokinetics in patients with Relapsed AML.

serum bilirubin level
tyrosine
remission
hematologic disorder
cytarabine
  • 0 views
  • 01 Jul, 2021
  • 1 location
Trial of Bortezomib, Cytarabine, and Dexamethasone in Mantle Cell Lymphoma (BATMAN)

The purpose of this study is to determine whether bortezomib, cytarabine, and dexamethasone are effective in the treatment of relapsed or refractory mantle cell lymphoma after 1 to 3 lines of

renal function tests
neutrophil count
mantle cell lymphoma
refractory mantle cell lymphoma
cytarabine
  • 13 views
  • 24 Feb, 2022
  • 1 location
Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia

This phase Ib trial investigates the side effects and best dose of pegcrisantaspase when given together with fludarabine and cytarabine for the treatment of patients with leukemia that has come

  • 0 views
  • 11 Mar, 2022
  • 1 location
Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

-care vinblastine/prednisone are used as front-line therapy while cytarabine therapy has been used as therapy for patients who develop recurrence. No alternate treatment strategy has been developed for

  • 12 views
  • 24 Feb, 2022
  • 5 locations
Fludarabine in Combination With Daunorubicin and Cytarabine Liposome in Newly-diagnosed Acute Myeloid Leukemia.

This phase 2 clinical trial will evaluate the effectiveness and safety of fludarabine in combination with CPX-351 in patients with untreated AML. Patients will receive fludarabine and CPX-351 during Induction 1 and 2 as well as 2 cycles of consolidation therapy.

  • 0 views
  • 08 Apr, 2021
  • 1 location
SKLB1028, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)

The purpose of this study is to describe the dose limiting toxicities (DLT) of SKLB1028 when combined with cytarabine/ daunorubicin remission induction in a 7+3 schedule. Safety and tolerability

  • 0 views
  • 22 Jul, 2022
  • 1 location
2157GCCC:Phase 1 of Calaspargase Pegol-mknl w/ Cytarabine and Idarubicin in Newly Dx AML

Characterizing the regimen limiting toxicity (RLT) of chemotherapeutic drug Calaspargase Pegol-mknl as remission induction and consolidation chemotherapy in patients with newly diagnosed Acute Myeloid Leukemia (AML) and Identifying the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of Calaspargase Pegol-mknl.

myelodysplastic syndromes
consolidation chemotherapies
remission
cytarabine
idarubicin
  • 0 views
  • 24 Mar, 2022
Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

This phase II trial studies how well venetoclax, cladribine, low dose cytarabine, and azacitidine work in treating patients with acute myeloid leukemia that has previously not been treated

venetoclax
cladribine
hematopoietic growth factors
hydroxyurea
neoadjuvant therapy
  • 19 views
  • 22 Mar, 2022
  • 1 location
Efficacy of HAD Induction With Intensified Cytarabine in Newly-diagnosed CEBPA Double Mutated Acute Myeloid Leukemia

(homoharringtonine(HHT)+cytarabine+daunorubicin) with intermediate dose cytarabine improved the survival of AML, especially in patients with CEBPA double mutation.

acute promyelocytic leukemia
acute leukemia
cancer
hematologic malignancy
cytarabine
  • 0 views
  • 15 Aug, 2021
  • 1 location