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Found 165 clinical trials
Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia, is the most frequent cancer in children and adolescents. Some genes have been described to produce drug resistance, as ABCB1 probably by lack of activation of AMPK. Some manuscripts have shown that metformin has antitumoral activity, mainly by activation of AMPK. This is an experimental one center …

  • 0 views
  • 06 May, 2022
  • 1 location
RWE of 1st Line Treatment in Adults With AML From 18 to 70 Years Old.

This is a multicenter, observational real world clinical trial with prospective follow up that will evaluate the treatment outcome of Acute Myeloid Leukemia (AML) patients in the first line with intensive chemotherapy based regimens in Argentina.

  • 5 views
  • 25 Nov, 2021
  • 2 locations
Ibrutinib Combined With R-CHOP/R-DHAP in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged ≤65 Years

The purpose of the study is to better and systematically collect clinical data on the treatment of ibrutinib combined with R-CHOP/DHAP regimen for more scientific and accurate evaluation, our center has carried out the R-CHOP/R-DHAP alternative regimen combined with ibrutinib at age ≤ An observational clinical study on the safety …

chop regimen
mantle cell lymphoma
ibrutinib
measurable disease
r-chop
  • 0 views
  • 11 Jul, 2022
  • 1 location
Pharmacokinetics of Venetoclax in Patients With Acute Myeloid Leukemia

Venetoclax is a treatment for chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). However, the pharmacokinetic data in Chinese population, as well as the change of venetoclax plasma concentration while taking CYP enzyme inducers or inhibitors, remained unknown so far. Therefore, the aim of this study is to investigate …

cancer
venetoclax
  • 0 views
  • 03 Nov, 2021
  • 1 location
RWE of Pediatric-like Protocol for AYA Patients With Ph-negative ALL

This is a multicenter, observational real world clinical trial with prospective follow up that will evaluate the treatment outcome of adolescent and young patients with ph-negative acute lymphoblastic leukemia with first-line pediatric-like protocol in Argentina.

  • 0 views
  • 26 Nov, 2021
  • 1 location