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Found 159 clinical trials
De-escalated Treatment Approach for Adult Ph-negative Acute Lymphoblastic Leukemia (ALL)

No high-dose methotrexate (MTX) and high-dose cytarabine (ARA-C) consolidation blocks, L-asparaginaseis scheduled for 1 year of treatment, 21 intrathecal injections through the whole treament, T

ara-c
adult t-cell leukemia/lymphoma
minimal residual disease
flow cytometry
cytarabine
  • 30 views
  • 28 Feb, 2022
  • 1 location
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage

, Decitabine, Venetoclax Combination Regimens) or Intensive Reinduction (High and Intermediate Dose Cytarabine Regimens), depending on the patient's prior induction treatment.

blast cells
ara-c
refractory acute myeloid leukemia (aml)
cytarabine/daunorubicin
azacitidine
  • 71 views
  • 16 Feb, 2022
  • 35 locations
Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia

leukemia cells can be unique to each patient and can change during the course of the disease. Chemotherapy drugs, such as cytarabine and daunorubicin work in different ways to stop the growth of cancer

serum bilirubin level
cancer
TP53
calcium
potassium
  • 0 views
  • 05 Oct, 2021
  • 1 location
Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia

that may have come back or is not responding to treatment. Drugs used in chemotherapy, such as cyclophosphamide, vincristine, dexamethasone, methotrexate, and cytarabine, work in different ways to stop

serum bilirubin level
serum lipase
cancer
chronic myeloid leukemia
cyclophosphamide
  • 13 views
  • 26 Mar, 2022
  • 1 location
Decitabine Combined With Unrelated Cord Blood Transplantation for Elderly Patients With AML

previous research, we will carry out the pretreatment regimen of decitabine + cytarabine in elderly patients with AML who have achieved disease treatment through induction therapy, and continue the

neoadjuvant therapy
cytarabine
umbilical cord blood transplantation
decitabine
consolidation therapy
  • 0 views
  • 03 Feb, 2022
  • 1 location
Low-Intensity Chemotherapy and Venetoclax in Treating Patients With Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia

, including vincristine, cyclophosphamide, dexamethasone, rituximab, methotrexate, and cytarabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from

  • 2 views
  • 25 Mar, 2022
  • 1 location
Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

chemotherapy, such as fludarabine, cytarabine, filgrastim and idarubicin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping

blast cells
cancer
refractory acute myeloid leukemia (aml)
venetoclax
filgrastim
  • 312 views
  • 29 Jan, 2022
  • 1 location
Combined Inhibition of PD-1 and DNA Hypomethylating Agent +/- Chemotherapy in High-risk AML or Elderly Patients With AML Who Are Unfit for Intensive Chemotherapy

This phase II trial studies how well tislelizumab combined with DNA hypomethylation agent +/- CAG regimen (cytarabine, idarubicin / Aclarithromycin, rhG-CSF/ PEG-rhG-CSF) work in treating

  • 0 views
  • 26 Jan, 2021
  • 1 location
A Study of Dasatinib Plus Reduced Intensive Consolidation Chemotherapy in Ph+ Adult ALL

regimen plus dasatinib, while the group B receives hyper-CVAD/methotrexate-cytarabine regimen plus dasatinib. The measurable residual disease (MRD), CR, adverse effects (AE), overall survival (OS) and

  • 0 views
  • 06 Oct, 2021
  • 1 location
Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma

substance and may kill cancer cells and shrink tumors. Chemotherapy drugs, such as carmustine, etoposide, cytarabine, and melphalan, work in different ways to stop the growth of tumor cells, either by

  • 0 views
  • 05 Apr, 2022
  • 1 location