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Found 183 clinical trials
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Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

either standard anthracycline therapy with mitoxantrone or experimental DaunoXome. In the second course patients are randomised between standard treatment with ADxE (cytarabine, DaunoXome, etoposide) or

  • 26 views
  • 21 Jan, 2021
  • 33 locations
None
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more …

methotrexate
dexamethasone
thioguanine
pegaspargase
combination chemotherapy
  • 1 views
  • 07 Nov, 2020
  • 5 locations
None
Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. A donor stem cell transplant may replace the patient's immune cells …

graft-versus-tumor
methotrexate
dexamethasone
thioguanine
asparaginase
  • 0 views
  • 07 Nov, 2020
  • 1 location
None
Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis

This study is testing whether stratification of the patients according to biological risk factors for different treatment groups will improve the outcome of patients with clinically high diffuse large B-cell lymphoma (DLBCL).

b-cell lymphoma
chemoimmunotherapy
follicular lymphoma
da-epoch
t-cell lymphoma
  • 36 views
  • 23 Jan, 2021
  • 18 locations
None
Comparing the Consolidation Regimens of IDA With Intermediate-dose Cytarabine Versus Intermediate-dose Cytarabine Alone for Elderly AML Patients

This study evaluates Idarubicin (IDA) in combination with the intermediate-dose cytarabine, compared with intermediate-dose cytarabine alone, as a consolidation treatment for elderly AML in

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX)

This is an open-label Phase I dose-escalation study of oral venetoclax in combination with increasing cytarabine doses plus mitoxantrone to define the safety profile and MTD of cytarabine in

cell transplantation
refractory acute myeloid leukemia (aml)
mitoxantrone
induction chemotherapy
acute promyelocytic leukemia
  • 0 views
  • 15 Sep, 2021
  • 5 locations
None
Cladribine Cytarabine and Idarubicin in Patients With Relapsed Acute Myelocytic Leukemia (AML)

The purpose of this study is to evaluate the safety and the efficacy of cladribine, high-dose cytarabine and idarubicin in the treatment of patients with relapsed acute myeloid leukemia.

cladribine
cytarabine
idarubicin
remission
  • 14 views
  • 07 Nov, 2020
  • 1 location
None
Fludarabine and Cytarabine as Continuous Infusion Plus G-CSF Priming for Elderly Patients With Resistant AML

- To determine the feasibility of fludarabine and cytarabine as continuous infusion plus granulocyte-colony stimulating factor priming for elderly patients with resistant acute

acute promyelocytic leukemia
fludarabine
cell transplantation
colony stimulating factor
granulocyte colony stimulating factor
  • 23 views
  • 07 Nov, 2020
  • 1 location
None
Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL

The aim of this study is to determine whether alternating courses of cyclophosphamide, doxorubicin, vincristine, prednisone/dexamethasone, cytarabine, cisplatin (CHOP/DHAP) plus rituximab

melphalan
rituximab
dexamethasone
measurable disease
vincristine
  • 135 views
  • 07 Nov, 2020
  • 2 locations
None
FLAG+Ida With G-CSF Priming for Patients Younger Than 60 Years With Resistant AML

- To determine the feasibility of fludarabine and cytarabine as continuous infusion plus idarubicin with granulocyte-colony stimulating factor priming for patients with resistant acute

idarubicin
fludarabine
colony stimulating factor
granulocyte colony stimulating factor
induction chemotherapy
  • 22 views
  • 07 Nov, 2020
  • 1 location