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Found 181 clinical trials
Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years

either standard anthracycline therapy with mitoxantrone or experimental DaunoXome. In the second course patients are randomised between standard treatment with ADxE (cytarabine, DaunoXome, etoposide) or

  • 26 views
  • 21 Jan, 2021
  • 33 locations
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more …

cancer
lymphoid leukemia
combination chemotherapy
methotrexate
pegaspargase
  • 1 views
  • 07 Nov, 2020
  • 5 locations
Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. A donor stem cell transplant may replace the patient's immune cells …

cancer
lymphoid leukemia
combination chemotherapy
methotrexate
daunorubicin
  • 0 views
  • 07 Nov, 2020
  • 1 location
Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis

This study is testing whether stratification of the patients according to biological risk factors for different treatment groups will improve the outcome of patients with clinically high diffuse large B-cell lymphoma (DLBCL).

t-cell lymphoma
chemoimmunotherapy
follicular lymphoma
b-cell lymphoma
large cell lymphoma
  • 32 views
  • 23 Jan, 2021
  • 18 locations
Comparing the Consolidation Regimens of IDA With Intermediate-dose Cytarabine Versus Intermediate-dose Cytarabine Alone for Elderly AML Patients

This study evaluates Idarubicin (IDA) in combination with the intermediate-dose cytarabine, compared with intermediate-dose cytarabine alone, as a consolidation treatment for elderly AML in

  • 0 views
  • 23 Jan, 2021
  • 1 location
Cladribine Cytarabine and Idarubicin in Patients With Relapsed Acute Myelocytic Leukemia (AML)

The purpose of this study is to evaluate the safety and the efficacy of cladribine, high-dose cytarabine and idarubicin in the treatment of patients with relapsed acute myeloid leukemia.

cytarabine
remission
idarubicin
cladribine
  • 14 views
  • 07 Nov, 2020
  • 1 location
Fludarabine and Cytarabine as Continuous Infusion Plus G-CSF Priming for Elderly Patients With Resistant AML

- To determine the feasibility of fludarabine and cytarabine as continuous infusion plus granulocyte-colony stimulating factor priming for elderly patients with resistant acute

cell transplantation
cytarabine
remission
induction chemotherapy
fludarabine
  • 23 views
  • 07 Nov, 2020
  • 1 location
Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX)

This is an open-label Phase I dose-escalation study of oral venetoclax in combination with increasing cytarabine doses plus mitoxantrone to define the safety profile and MTD of cytarabine in

mitoxantrone
cytarabine
induction chemotherapy
cell transplantation
refractory acute myeloid leukemia (aml)
  • 0 views
  • 15 Sep, 2021
  • 2 locations
Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL

The aim of this study is to determine whether alternating courses of cyclophosphamide, doxorubicin, vincristine, prednisone/dexamethasone, cytarabine, cisplatin (CHOP/DHAP) plus rituximab

vincristine
measurable disease
ara-c
rituximab
cell transplantation
  • 134 views
  • 07 Nov, 2020
  • 2 locations
FLAG+Ida With G-CSF Priming for Patients Younger Than 60 Years With Resistant AML

- To determine the feasibility of fludarabine and cytarabine as continuous infusion plus idarubicin with granulocyte-colony stimulating factor priming for patients with resistant acute

cytarabine
idarubicin
induction chemotherapy
fludarabine
colony stimulating factor
  • 22 views
  • 07 Nov, 2020
  • 1 location