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Found 217 clinical trials
Featured trial
A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

  • 588 views
  • 07 Nov, 2020
  • 1 location
Featured trial
Role of Genetic Factors in the Pathogenesis of Lung Disease

older with CF. Children will not be enrolled in the optional CT sub-study unless they have had a standard CT scan for medical purposes to use in comparison. One additional low dose radiation CT scan of

pulmonary disease
bronchoscopy
pulmonary fibrosis
diabetes
  • 358 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of …

aplastic anemia
anemia studies
myelodysplastic syndromes
myelodysplastic syndrome (mds)
  • 57 views
  • 22 Dec, 2020
  • 1 location
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib Administered Once Daily for 52 Weeks in Subjects With Non-Cystic Fibrosis Bronchiectasis - The ASPEN Study (ASPEN)

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

  • 168 views
  • 27 Oct, 2022
  • 327 locations
Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis

The purpose of this study is to determine whether potentiating the cystic fibrosis transmembrane conductance regulator (CFTR) with QBW251 in patients with bronchiectasis will demonstrate

mucolytics
chest physiotherapy
cystic fibrosis
combinations
grip
  • 6 views
  • 07 Oct, 2022
  • 16 locations
Prednisone in Cystic Fibrosis Pulmonary Exacerbations (PIPE)

This will be a 5 year randomized, double blind, placebo controlled trial of 7 days of oral prednisone in cystic fibrosis (CF) patients receiving intravenous (IV) antibiotic treatment for a

  • 38 views
  • 03 Mar, 2022
  • 12 locations
Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD.

To determine the efficacy of nebulized 5% hypertonic saline on cough severity and quality of life, in children with non-CF CSLD. Secondary Aims: To determine the:

cough
antibiotics
  • 0 views
  • 24 May, 2022
  • 1 location
Comparison of Meal-Time Dosing of Insulin in Cystic Fibrosis Related Diabetes

The aim of this study is to assess the utility of CGMs to determine the optimal method to dose meal-time insulin. The investigators will examine glucose excursions in patients with CF who will

  • 13 views
  • 07 Oct, 2022
  • 1 location
IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study) (ABATE)

The purpose of this study is to assess the safety and tolerability of two 5-day infusion cycles of IV gallium in adult patients with CF who are infected with NTM. Funding Source - FDA

  • 0 views
  • 15 Mar, 2022
  • 5 locations
  • 0 views
  • 15 Feb, 2022
  • 1 location