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Found 197 clinical trials
Featured trial
A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

  • 588 views
  • 07 Nov, 2020
  • 1 location
Featured trial
Role of Genetic Factors in the Pathogenesis of Lung Disease

This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes …

pulmonary fibrosis
pulmonary disease
diabetes
bronchoscopy
  • 352 views
  • 23 Nov, 2020
  • 1 location
Efficacy and Safety of Benralizumab in Patients With Non-cystic Fibrosis Bronchiectasis (MAHALE)

placebo on top of standard-of-care therapy in adult patients with non-cystic fibrosis bronchiectasis with eosinophilic inflammation (NCFB+EI). All patients who complete the 52-week double-blind

  • 8 views
  • 06 May, 2022
  • 47 locations
A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis (ASPEN)

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

  • 75 views
  • 15 May, 2022
  • 355 locations
Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis

The purpose of this study is to determine whether potentiating the cystic fibrosis transmembrane conductance regulator (CFTR) with QBW251 in patients with bronchiectasis will demonstrate

cough
cystic fibrosis
grip
pulmonary function test
chest physiotherapy
  • 6 views
  • 22 Apr, 2022
  • 14 locations
Prednisone in Cystic Fibrosis Pulmonary Exacerbations (PIPE)

This will be a 5 year randomized, double blind, placebo controlled trial of 7 days of oral prednisone in cystic fibrosis (CF) patients receiving intravenous (IV) antibiotic treatment for a

  • 38 views
  • 03 Mar, 2022
  • 12 locations
Effectiveness of the Hippotherapy Simulator in Children With Cystic Fibrosis

Cystic fibrosis (CF) is a genetic disease that affects many organs and systems, especially respiratory system problems due to lung damage. Patients often have difficulty in removing the sticky

  • 0 views
  • 26 Apr, 2022
  • 1 location
Home Airway Clearance in CF Patients

Regular bronchial clearance is essential in patients with cystic fibrosis for their bronchial health. SIMEOX (Physio-Assist, Aix en Provence, France) is an innovative medical device for the

  • 2 views
  • 25 Aug, 2021
  • 6 locations
An Open-label, Phase 1/2 Trial of Gene Therapy 4D-710 in Adults With Cystic Fibrosis (CF)

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with CF who are ineligible for or unable to tolerate CFTR modulator therapy.

cftr gene
cystic fibrosis transmembrane conductance regulator
forced expiratory volume
oximetry
  • 0 views
  • 15 Mar, 2022
  • 1 location
  • 0 views
  • 15 Feb, 2022
  • 1 location