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Found 291 clinical trials
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A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

  • 574 views
  • 07 Nov, 2020
  • 1 location
featured
A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis (ASPEN)

This study will investigate the efficacy, safety, and tolerability of brensocatib in the clinical management of subjects with Non-Cystic Fibrous Bronchiectasis (NCFBE).Subjects will be randomized in a 1:1:1 ratio to 3 treatment arms to receive brensocatib 10 mg once daily (QD), brensocatib 25 mg QD, or matching placebo QD for …

bronchiectasis
  • 0 views
  • 28 Jun, 2021
  • 1 location
featured
Role of Genetic Factors in the Pathogenesis of Lung Disease

older with CF. Children will not be enrolled in the optional CT sub-study unless they have had a standard CT scan for medical purposes to use in comparison. One additional low dose radiation CT scan of

pulmonary disease
diabetes
pulmonary fibrosis
bronchoscopy
  • 120 views
  • 23 Nov, 2020
  • 1 location
featured
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of …

anemia studies
myelodysplastic syndrome (mds)
myelodysplastic syndromes
aplastic anemia
  • 57 views
  • 22 Dec, 2020
  • 1 location
Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium (PROMIS II)

subjects with non-cystic fibrosis bronchiectasis (NCFB) chronically infected with P. aeruginosa on the frequency of pulmonary exacerbations.

  • 155 views
  • 24 Jan, 2021
  • 108 locations
A Study to Assess the Efficacy Safety and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

  • 0 views
  • 28 Jul, 2021
  • 254 locations
Prednisone in Cystic Fibrosis Pulmonary Exacerbations

This will be a 5 year randomized, double blind, placebo controlled trial of 7 days of oral prednisone in cystic fibrosis (CF) patients receiving intravenous (IV) antibiotic treatment for a

  • 32 views
  • 19 Jun, 2021
  • 12 locations
Ghrelin in Cystic Fibrosis

reduce inflammation within the body. Cystic Fibrosis (CF) is a genetic disease which frequently results in recurrent lung infections (leading to progressive inflammatory lung damage) and low

genetic disorder
pulmonary function test
cancer
  • 9 views
  • 07 Nov, 2020
  • 1 location
EnVision CF Multicenter Study of Glucose Tolerance in Cystic Fibrosis

Cystic Fibrosis Related Diabetes has been identified by the CF community as one of the top ten priorities for CF research. In CF clinical decline due to dysglycemia begins early, prior to

  • 0 views
  • 24 Jan, 2021
  • 1 location
Home Airway Clearance in CF Patients

Regular bronchial clearance is essential in patients with cystic fibrosis for their bronchial health. SIMEOX (Physio-Assist, Aix en Provence, France) is an innovative medical device for the

  • 0 views
  • 02 Feb, 2021
  • 6 locations