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Found 570 clinical trials
INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS

, donors could undergo a second PB collection within 30 days from the first one. Patients will receive immunosuppressive chemotherapy, fludarabine (Flu) 25 mg/mq/ from day -7 to -3 and cyclophosphamide (Cy

leukapheresis
cyclophosphamide
immunosuppressants
fludarabine
cell transplantation
  • 0 views
  • 03 Feb, 2021
  • 1 location
Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis.

shown to be as effective as cyclophosphamide to induce remission and maintenance of remission in severe GPA and MPA patients, with an acceptable safety profile . Although rituximab is becoming the

  • 0 views
  • 23 Jan, 2021
  • 57 locations
Exposure of Taxi Drivers to Ultrafine Particles and Black Carbon Within Their Vehicles

is to determine whether prednisone, methotrexate, and cyclophosphamide are effective in the treatment of rapidly progressive hearing loss in both ears due to autoimmune inner ear disease (AIED). This

  • 0 views
  • 22 Jan, 2021
  • 1 location
Study Evaluating the Safety and Efficacy of C-CHOP in Untreated Subjects With Angioimmunoblastic T Cell Lymphoma

This is a single-arm, open-label phase 2study of Chidamide in combination with CHOP in the treatment of subjects with untreated angioimmunoblastic T cell lymphoma.

prednisone
vincristine
lymphoma
doxorubicin
cyclophosphamide
  • 0 views
  • 23 Jan, 2021
Trial to Compare the Efficacy and Safety Of MW05 and PEG-rhG-CSF

In the study, subjects will scheduled to undergo four 21-days cycles of chemotherapy treatment. Three group were treated with MW05 300 g/kg or MW05 500 g/kg or PEG-rhG-CSF 100 g/kg on the 3th day of each cycle randomized 1:1:1 . The dose of the experimental drug MW05 in phase III …

  • 0 views
  • 26 Jan, 2021
  • 1 location
TCD Followed by autoSCT for Newly Diagnosed MM Patients

Multiple Myeloma is a incurable disease. Thalidomide in combination with other agents are currently in trials for the newly diagnosed patients, we designed treatment of TCD, followed by high dose chemotherapy with autologous stem cell transplantation and TD maintenance therapy for the patients with newly diagnosed multiple myeloma.

high dose chemotherapy
maintenance therapy
thalidomide
cell transplantation
  • 5 views
  • 07 Nov, 2020
  • 1 location
Irinotecan and Temozolomide for Ewing Sarcoma

The investigators explored the activity of vincristine and irinotecan combined with temozolomide (VIT) in patients with relapsed and metastatic Ewing Sarcoma.

immunosuppressive
vincristine
temozolomide
cell transplantation
ifosfamide
  • 55 views
  • 22 Jan, 2021
  • 1 location
CD19-CAR-T in B-cell Malignancies Patients

This is a single center, single arm, open-lable phase I study to determine the safety and efficacy of CD19-CAR-T cells in patients with refractory and relapsed B-cell malignancies.

  • 2 views
  • 24 Jan, 2021
  • 1 location
CD19-Synthetic T Cell Antigen Receptor(STAR)-T in B-cell Malignancies Patients

This is a single center, single arm, open-lable phase I study to determine the safety and efficacy of CD19-STAR-T cells in patients with refractory and relapsed B-cell malignancies (such as NHL and ALL ).

  • 0 views
  • 25 Jan, 2021
  • 1 location
Low Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome

The aim of the current study is to evaluate the safety and efficacy of low dose treosulfan based conditioning regimen in HSCT in Nijmegen breakage syndrome

  • 0 views
  • 25 Jan, 2021
  • 1 location