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Found 563 clinical trials
Epacadostat Pembrolizumab and CRS-207 With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas Cancer

/pembrolizumab/cyclophosphamide(CY)/GVAX pancreas vaccine followed by epacadostat/pembrolizumab/CRS-207, Part 1X (dose escalation) participants will receive epacadostat/pembrolizumab/CRS-207. Part 2X (dose

metastatic pancreatic cancer
measurable disease
cancer
pembrolizumab
  • 2 views
  • 19 Feb, 2021
  • 1 location
Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma

after non-myeloablative chemotherapy with cyclophosphamide and fludarabine. TIL transfer will be combined with low dose Interleukin (IL)-2 and nivolumab anti-PD-1 treatment. The study uses a

interleukin
neutrophil count
metastasis
gilbert's syndrome
liver metastasis
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Novel TBI Free Conditioning Protocol for Haploidentical Transplant in Acquired Aplastic Anemia:

. Haploidentical transplant represents only curative option for patients lacking MSD. Protocols involving post transplant cyclophosphamide require Total body irradiation (TBI) and utilize peripheral blood stem

  • 4 views
  • 24 Jan, 2021
  • 2 locations
Randomised Prospective Comparison of the NMA Allograft and the Traditional Allograft in Acute Myeloid Leukaemia

The allograft of marrow in its technique of reference (myélo-ablative (MA) condition by cyclophosphamide and total body irradiation (TBI) with strong amounts) therapeutic is recognized

remission
secondary acute myeloid leukemia
idarubicin
cyclophosphamide
daunorubicin
  • 18 views
  • 07 Nov, 2020
  • 1 location
Adoptive Immunotherapy of High Risk Acute Myeloblastic Leukemia Patients Using Haploidentical Kir Ligand-mismatched Natural Killer Cells

cyclophosphamide 4g/m2 (Flu/Cy). The therapy will be administered over 6 days on inpatient basis. Haploidentical NK cells will be selected from a steady-state large volume leukapheresis product from a

  • 9 views
  • 07 Nov, 2020
  • 1 location
Allogeneic Blood Stem Cell Transplantation for Patients With Life-Threatening Systemic Lupus Erythematosus

erythematosus (SLE) that is resistant to standard treatment (prednisone and cyclophosphamide [Cytoxan]) into a new study to determine if they can be successfully treated with a blood stem cell

immunosuppressive agents
nephritis
cyclophosphamide
oral cyclophosphamide
corticosteroids
  • 34 views
  • 07 Nov, 2020
  • 1 location
Daratumumab Intensified Treatment to Eligible MM New Patients CTD-Dara Induction Follow by Dara Consolidation

drugs combo did not prove gain against three drugs One of the three drugs protocol studied as induction was CTD scheme (cyclophosphamide+ thalidomide+dexamethasone). Daratumumab has a novel mechanism of

  • 0 views
  • 22 Jan, 2021
  • 1 location
Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

transplant. Donors receiving haploidentical related donors will receive two doses of chemotherapy with cyclophosphamide, 5 days of fludarabine, 3 days of busulfan, and one dose of radiation to suppress their

  • 1 views
  • 04 Mar, 2021
  • 1 location
INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS

, donors could undergo a second PB collection within 30 days from the first one. Patients will receive immunosuppressive chemotherapy, fludarabine (Flu) 25 mg/mq/ from day -7 to -3 and cyclophosphamide (Cy

fludarabine
cell transplantation
cyclophosphamide
immunosuppressants
leukapheresis
  • 0 views
  • 03 Feb, 2021
  • 1 location
Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis.

shown to be as effective as cyclophosphamide to induce remission and maintenance of remission in severe GPA and MPA patients, with an acceptable safety profile . Although rituximab is becoming the

  • 0 views
  • 23 Jan, 2021
  • 57 locations