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Found 561 clinical trials
Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab Busulfan and TBI With Post-Transplant Cyclophosphamide

Background CGD causes infections and inflammation. The only cure currently is a bone marrow transplant. Most often a perfectly matched bone marrow donor is used. Researchers want to see if they can lower the risks of using a mismatched donor. Objectives To see if it is safe to use a …

busulfan
sirolimus
stem cell transplantation
cyclophosphamide
bone marrow transplant
  • 1 views
  • 27 Apr, 2021
  • 1 location
Reduced Toxicity Fludarabine (Flu) + Cyclophosphamide (CPM) + Rabbit Antithymocyte Globulin (rATG) Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia (SAA)

reported to be promising for transplantation from alternative donors in SAA, thymoglobulin was added to fludarabine and cyclophosphamide conditioning to reduce GVHD and to allow good engraftment

thymoglobulin
cell transplantation
neutrophil count
fludarabine
total body irradiation
  • 26 views
  • 07 Nov, 2020
  • 1 location
Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL

The aim of this study is to determine whether alternating courses of cyclophosphamide, doxorubicin, vincristine, prednisone/dexamethasone, cytarabine, cisplatin (CHOP/DHAP) plus rituximab

granulocyte colony stimulating factor
cell transplantation
rituximab
melphalan
measurable disease
  • 134 views
  • 07 Nov, 2020
  • 2 locations
BCD Regimen in Newly Diagnosed Idiopathic Multicentric Castleman's Disease (iMCD)

To explore the effectiveness and safety of bortezomib, cyclophosphamide and dexamethasone (BCD regimen) in newly diagnosed idiopathic Multicentric Castleman's disease (iMCD) patients.

  • 1 views
  • 23 Jan, 2021
  • 1 location
Chidamide Combined With CHOPE Regimen for Peripheral T-cell Lymphoma Patients

Chidamide With Cyclophosphamide, Doxorubicin, Vincristine, Prednisone and Etoposide for Peripheral T Cell Lymphoma Patients : a Prospective, Randomized Controlled, Open Label, Phase II Clinical

  • 5 views
  • 22 Jan, 2021
  • 1 location
Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML)

The investigators hypothesize that long-term disease-free survival (DFS) in patients with JMML can be achieved with a treatment of busulfan (BU), cyclophosphamide (CY) and melphalan (L-PAM

cell transplantation
melphalan
ejection fraction
busulfan
monocytosis
  • 4 views
  • 02 Jun, 2021
  • 1 location
Post Transplant High-Dose Cy as GvHD Prophylaxis in 1 HLA Mismatched Unrelated HSCT for Myeloid Malignancies

The experimental treatment consists in the application of a therapeutic strategy with post Transplant High-Dose Cyclophosphamide as GvHD Prophylaxis in Patients Receiving 1-Antigen/Allele HLA

  • 0 views
  • 26 Mar, 2021
  • 33 locations
Study on TIL for the Treatment of r/r Gynecologic Tumors

expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodepletion treatment with fludarabine and cyclophosphamide.

  • 0 views
  • 28 Feb, 2021
  • 1 location
Safety and Efficacy of ALLO-715 BCMA Allogenic CAR T Cells in in Adults With Relapsed or Refractory Multiple Myeloma (UNIVERSAL)

myeloma after a lymphodepletion regimen of ALLO-647 in combination with fludarabine and/or cyclophosphamide, or ALLO-647 alone.

  • 4 views
  • 07 Jun, 2021
  • 12 locations
Chidamide Plus CHOEP Combined With Upfront ASCT in Untreated Peripheral T-cell Lymphoma

The purpose of this study is to determine determine the maximum tolerated dose (MTD) and safety of the combination of Chidamide combined with CHOEP(cyclophosphamide epirubicin,vindesine

peripheral t-cell lymphoma
prednisone
etoposide
measurable disease
cyclophosphamide
  • 3 views
  • 21 Jan, 2021
  • 1 location