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Found 562 clinical trials
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Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the complications for these procedures. This might allow more people to have a transplant. Objective: To see if a new transplant regime is effective, safe and well …

cell transplantation
sickle cell disease
stroke
red blood cell disorder
  • 57 views
  • 22 Dec, 2020
  • 1 location
featured
Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

Rituximab plus Belimumab for Lupus Nephritis (CALIBRATE Study)

  • 926 views
  • 08 Nov, 2020
  • 12 locations
featured
A Phase 2 Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of Tcelna in Subjects With Secondary Progressive Multiple Sclerosis

A Phase 2 Double-Blind, Placebo Controlled Multi-Center Study to Evaluate the Efficacy and Safety of Tcelna in Subjects With Secondary Progressive Multiple Sclerosis

  • 204 views
  • 08 Nov, 2020
  • 1 location
featured
A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

  • 74 views
  • 08 Nov, 2020
  • 1 location
Pomalidomide-Cyclophosphamide-Dexamethasone (PCD) Versus Pomalidomide-Dexamethasone (PD) in Relapse or Refractory Myeloma

safety profile. More important for patients with suboptimal response to PD will achieve a clinically meaningful response with the addition of oral cyclophosphamide (PCD). In the United States, a small

cancer
dexamethasone
hysterectomy
bortezomib
induction therapy
  • 33 views
  • 21 Jan, 2021
  • 3 locations
Evaluation of Maxy-G34 in Breast Cancer Patients Treated With TAC (Docetaxel Adriamycin Cyclophosphamide) Chemotherapy

This is an investigation of the safety and efficacy of Maxy-G34 in breast cancer patients treated with TAC chemotherapy. Maxy-G34 will be given as a single injection during each cycle of chemotherapy, for a planned total of six chemotherapy cycles.

immunostimulant
anthracyclines
adriamycin
cyclophosphamide
docetaxel
  • 68 views
  • 07 Nov, 2020
  • 1 location
A Trial Looking at Ofatumumab for People With Chronic Lymphocytic Leukaemia Who Cannot Have More Intensive Treatment

enough for rituximab, fludarabine & cyclophosphamide (R-FC).

chronic lymphocytic leukemia
fludarabine
ofatumumab
thrombocytopenia
bendamustine
  • 436 views
  • 08 Nov, 2020
  • 1 location
Neoadjuvant Chemotherapy for Operable Premenopausal Breast Cancer Patients

docetaxel plus epirubicin, and docetaxel plus epirubicin plus cyclophosphamide as neoadjuvant chemotherapy for operable premenopausal breast cancer patients, and also to compare the outcomes associated with

  • 0 views
  • 21 Jan, 2021
  • 13 locations
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more …

cytarabine
cancer
thioguanine
dexamethasone
lymphoid leukemia
  • 1 views
  • 07 Nov, 2020
  • 5 locations
Combination Chemotherapy and Trastuzumab in Treating Women With Stage I Stage II or Stage III HER2-Positive Breast Cancer

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. …

adjuvant therapy
trastuzumab
paclitaxel
immunostimulant
epirubicin
  • 33 views
  • 07 Nov, 2020
  • 1 location