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Found 550 clinical trials
Featured trial
A Phase 2 Study to Investigate the Safety and Efficacy of ABBV-105 and Upadacitinib Given Alone or in Combination (ABBV-599 Combination) in Subjects with Moderately to Severely Active Systemic Lupus Erythematosus

The purpose of this study is to see if the study drugs, ABBV-105, upadacitinib (ABT-494), or both ABBV-105 and upadacitinib (ABT-494) in combination (ABBV-599) are safe, tolerable, and effective in treating your moderately to severely active systemic lupus erythematosus (SLE).  

prednisone
cyclosporine
  • 155 views
  • 23 Nov, 2020
  • 1 location
Featured trial
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Gene transfer is a new cancer therapy takes white blood cells from a person and grows them in a lab. The cells are changed with a virus to attack tumor cells, then returned to the person. Researchers want to see if this therapy fights kidney cancer cells. Metastatic renal cell …

metastatic cancer
clear cell renal cell carcinoma
clear cell carcinoma
renal cell cancer
primary cancer
  • 208 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Haplo-identical Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using Peripheral Blood Stem Cells and Post-Transplant Cyclophosphamide for GVHD Prophylaxis

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MD) cause serious blood problems. Stem cell transplants using bone marrow or blood plus chemotherapy can help. Researchers want to see if using peripheral blood stem cells (PBSCs) rather than bone marrow cells works too. PBSCs are easier to collect and have …

anemia
aplastic anemia
myelodysplastic syndrome (mds)
anemia studies
myelodysplastic syndromes
  • 75 views
  • 22 Dec, 2020
  • 1 location
Featured trial
AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

  • 380 views
  • 08 Nov, 2020
  • 1 location
Featured trial
  • 306 views
  • 08 Nov, 2020
  • 1 location
Featured trial
Featured trial
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

medicines, for transfusions of red blood cells and platelets, and for collecting blood samples. Preparatory chemotherapy (fludarabine, cyclophosphamide and anti-thymocyte globulin) and total body

anemia
aplastic anemia
myelodysplastic syndrome (mds)
anemia studies
myelodysplastic syndromes
  • 54 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

of the National Institutes of Health Clinical Center and will receive regular doses of cyclophosphamide, fludarabine, and anti-thymocyte globulin to suppress their immune system and prepare for the

anemia
aplastic anemia
myelodysplastic syndrome (mds)
anemia studies
myelodysplastic syndromes
  • 190 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the complications for these procedures. This might allow more people to have a transplant. Objective: To see if a new transplant regime is effective, safe and well …

sickle cell disease
cell transplantation
red blood cell disorder
stroke
  • 83 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Spectrum Neutropenia in Breast Cancer

Spectrum Neutropenia in Breast Cancer

  • 238 views
  • 08 Nov, 2020
  • 1 location