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Found 72 clinical trials
Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site

This phase II trial tests whether atezolizumab works to shrink tumors before surgery in patients with head and neck squamous cell cancer with an unknown or historic primary site that has spread to other places in the lymph nodes (regionally metastatic). Immunotherapy with monoclonal antibodies, such as atezolizumab, may help …

  • 0 views
  • 24 Mar, 2022
  • 1 location
A Study of SBRT for Squamous Cell Carcinoma of the Head and Neck

To evaluate the tumour response rate of squamous cell carcinoma of the head and neck following stereotactic body radiotherapy (SBRT) of 45Gy in 5 fractions delivered once every 3-4 days, such that treatment is completed within 15 days.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Study of Metabolic Changes in the Transformation Malignant Precancerous Skin Lesions (MITOSKIN)

Skin carcinomas are the most frequent cancers in the world, including basal cell carcinomas and cutaneous squamous cell carcinoma (cSCCs), with more than 60.000 new annual cases in France. Their

actinic keratosis
cancer
metastasis
skin lesion
skin lesions
  • 0 views
  • 24 May, 2022
A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumors

The investigator believes that injecting Copaxone into tumors will help participants immune system fight cancer. This has been studied in mice and has shown encouraging results. Copaxone is a safe medication currently used to treat Multiple Sclerosis (MS) and has very few side effects. To be considered for this trial …

carcinoma
cancer
squamous cell carcinoma
copaxone
  • 2 views
  • 24 May, 2022
  • 3 locations
ASP-1929 Photoimmunotherapy (PIT) Study in in Patients With Recurrent Head/Neck Cancer

Cutaneous Squamous Cell Carcinoma

measurable disease
cancer
neck cancer
carcinoma
squamous cell carcinoma
  • 0 views
  • 05 Jun, 2022
  • 1 location
A PD-1 Checkpoint Inhibitor (Cemiplimab) for High-Risk Localized Locally Recurrent or Regionally Advanced Skin Cancer

This phase II trial studies how well cemiplimab before surgery works in treating patients with skin cancer that is high-risk and has not spread to other parts of the body (localized), has come back locally (locally recurrent), or has spread regionally (regionally advanced), and can be removed by surgery (resectable). …

  • 0 views
  • 25 Oct, 2021
  • 3 locations
Study of TVEC in Patients With Cutaneous Squamous Cell Cancer

This is single arm a Phase 2, single center study of talimogene laherparepvec (TVEC) to treat low risk cutaneous squamous cell carcinomas (cSCC).

platelet count
anticoagulants
skin cancer
cancer
anticoagulant therapy
  • 15 views
  • 21 Apr, 2022
  • 2 locations
Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders (MITRIC)

This is a single-arm, single-center, open-label, phase IIa study evaluating the safety, feasibility and efficacy of Faecal Microbiota Transplant (FMT) to cancer patients not responding to ICI therapy, using ICI-responders as donors.

platelet count
cancer
programmed cell death 1 ligand 1
measurable disease
progressive disease
  • 0 views
  • 07 Apr, 2022
  • 1 location
CMP-001 in Combination With IV PD-1-Blocking Antibody in Subjects With Certain Types of Advanced or Metastatic Cancer

CMP-001-009 is a Phase 2 study of intratumoral CMP-001 in combination with an intravenous PD-1-blocking antibody administered to participants with certain types of advanced or metatastic cancer. The primary objective of the study is to determine the Investigator-assessed confirmed objective response with CMP-001 in combination with a programmed cell death …

cancer
  • 0 views
  • 28 Jul, 2022
  • 13 locations
Study of NKTR 255 in Combination With Cetuximab in Solid Tumors

carcinoma (CRC), cutaneous squamous cell carcinoma (cSCC), anal cell carcinoma (ASCC) and cervical cancer. The recommended phase 2 dose of NKTR-255, determined in the dose escalation phase (Phase 1b), will

measurable disease
cetuximab
antiretroviral
squamous cell carcinoma
carcinoma
  • 2 views
  • 26 Apr, 2022
  • 11 locations