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Found 49 clinical trials
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A Prospective, Observational, US-based Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell Lymphoma and Treated With Valchlor®

A Prospective, Observational, US-based Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell Lymphoma and

  • 538 views
  • 23 Nov, 2020
  • 1 location
A Study of ABT-199 (Venetoclax) for Cutaneous T Cell Lymphoma (CTCL)

The objective of this study are to evaluate the safety and tolerability of ABT-199 (venetoclax) in patients with advanced Cutaneous T cell lymphoma (CTCL). A secondary objective is to explore

romidepsin
systemic therapy
electron beam therapy
extracorporeal photopheresis
sezary syndrome
  • 3 views
  • 29 Jan, 2021
  • 1 location
Open-label Pilot Study of Lenalidomide (Revlimid) as Adjuvant Treatment for Refractory Cutaneous T Cell Lymphoma

Patients with cutaneous T cell lymphoma experience refractory and progressive disease despite current treatment, necessitating chronic disease management. In addition, there needs to be

lenalidomide
extracorporeal photopheresis
sezary syndrome
neutrophil count
mycosis
  • 112 views
  • 08 Nov, 2020
  • 1 location
Tazarotene 0.1% Cream For the Treatment of Cutaneous T-Cell Lymphoma: A Prospective Study

This is an open label, prospective study to evaluate therapeutic potential of Tazarotene 0.1% cream for the treatment of Stage I-IIA CTCL. Patients with Stage I-IIA disease are enrolled

mycosis
lymphoma
  • 0 views
  • 07 Nov, 2020
  • 1 location
BI-1808 as a Single Agent and With Pembrolizumab in Treatment of Advanced Malignancies

iRECIST can be applied for efficacy assessment) and subjects with cutaneous T-cell lymphoma (CTCL), specifically Szary Syndrome (SS) and mycosis fungoides (MF). The study will consist of 2 phases

  • 0 views
  • 03 May, 2021
  • 8 locations
Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or S zary Syndrome (SS)

The purpose of this study is to determine whether resminostat will be able to delay or prevent worsening of disease in patients with advanced stage mycosis fungoides or Szary Syndrome that have recently achieved disease control with previous systemic therapy.

renal function test
systemic therapy
sezary syndrome
maintenance treatment
chemotherapy regimen
  • 898 views
  • 10 Apr, 2021
  • 92 locations
IPH4102 Alone or in Combination With Chemotherapy in Patients With Advanced T Cell Lymphoma

This is an open label, multi-cohort, and multi-center phase II study, which evaluates the clinical activity and safety of IPH4102 in Sezary Syndrome and Mycosis fungoides as single agent.

systemic therapy
angioimmunoblastic t-cell lymphoma
beta-hcg
large cell lymphoma
anaplastic large cell lymphoma
  • 26 views
  • 26 Jan, 2021
  • 36 locations
Study of Tinostamustine First-in-Class Alkylating HDACi Fusion Molecule in Relapsed/Refractory Hematologic Malignancies

This study evaluates the efficacy, safety and pharmacokinetics of tinostamustine (EDO-S101) in patients with relapsed/refractory hematologic malignancies. All patients will receive tinostamustine.

potassium
t-cell prolymphocytic leukemia
refractory multiple myeloma
angioimmunoblastic t-cell lymphoma
leukemia
  • 0 views
  • 27 Jan, 2021
  • 25 locations
Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

This partially randomized clinical trial studies cholecalciferol in improving survival in patients with newly diagnosed cancer with vitamin D insufficiency. Vitamin D replacement may improve tumor response and survival and delay time to treatment in patients with cancer who are vitamin D insufficient.

panniculitis
rituximab
b-cell lymphoma
cyclin d1
extranodal nk/t-cell lymphoma, nasal type
  • 87 views
  • 13 Apr, 2021
  • 2 locations
Micro Needle Array-Doxorubicin (MNA-D) in Patients With Cutaneous T-cell Lymphoma (CTCL)

-specific immunity. The purpose of this study is to test a new method of experimental treatment for CTCL, using small adhesive-like patches (a micro-needle applicator or MNA for short), which have

skin biopsy
extracorporeal photopheresis
tumor cells
topical steroids
bexarotene capsules
  • 23 views
  • 27 Jan, 2021
  • 1 location