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Found 14 clinical trials
Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus (CLEan)

Primary Objective: Assess the efficacy of SAR443122 in cutaneous lupus erythematosus (CLE) Secondary Objectives: Assess the effect of SAR443122 on the

  • 19 views
  • 24 Jun, 2022
  • 53 locations
Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus (CLEan)

Primary Objective: Assess the efficacy of SAR443122 in cutaneous lupus erythematosus (CLE) Secondary Objectives: Assess the effect of SAR443122 on the

  • 3 views
  • 28 Jun, 2022
  • 53 locations
A Study to Evaluate Efficacy and Safety of BMS-986165 in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)

The purpose of this study is to assess the safety, efficacy, and tolerability of BMS-986165 compared with placebo in participants with active discoid and/or subacute cutaneous lupus

  • 7 views
  • 29 Jun, 2022
  • 24 locations
Study of M5049 in CLE and SLE Participants

This study is to evaluate the safety, tolerability and pharmacokinetics (PK) of orally administered M5049 in participants with systemic lupus erythematosus (SLE) or cutaneous lupus erythematosus

cutaneous lupus
lupus
  • 0 views
  • 28 Jun, 2022
  • 10 locations
The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW)

(SLE) and cutaneous lupus erythematosus (CLE; subacute cutaneous lupus erythematosus [SCLE] and/or discoid lupus erythematosus [DLE]) participants in a randomized, double-blind, placebo-controlled

cutaneous lupus
estrogen
corticosteroids
lupus
  • 0 views
  • 30 Jun, 2022
  • 16 locations
Low-dose UVA1 Radiation in Cutaneous Lupus Patients

The investigators are conducting an open-label clinical trial determining the effects of UVA1 phototherapy on cutaneous lupus (CLE) patients. Past research on systemic lupus (SLE) subjects

phototherapy
  • 48 views
  • 10 Mar, 2022
  • 1 location
A Study to Assess the Safety and Drug Levels of BMS-986256 in Participants With Active Cutaneous Lupus Erythematosus

The purpose of this study is to assess the safety and drug levels of BMS-986256 in participants with cutaneous lupus erythematosus.

drug levels
systemic lupus erythematosus
skin lesion
  • 0 views
  • 12 May, 2022
  • 1 location
Efficacy and Safety of Topical Nicotinamide in Treatment of Discoid Lupus Erythematosus

Cutaneous lupus erythematosus (CLE) is lupus affecting the skin. In this autoimmune disease, the body's immune system attacks healthy skin. There are 3 main types: Acute cutaneous lupus

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Evaluation of Tofacitinib in Prevention of Photosensitivity in Lupus

This is a single-arm, single-site, proof-of-concept study that will evaluate the treatment of 10 participants with systemic lupus erythematosus (SLE) who have a history of cutaneous lupus with

  • 0 views
  • 12 May, 2022
  • 1 location
Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus

This 76-week, 3-part Phase 1b/2 study is intended to evaluate the pharmacological properties (pharmacokinetics and pharmacodynamics), safety, tolerability and preliminary effectiveness of TOFA administrated to young adults (18-45 years) with moderately to severely active SLE-CL. Subjects will be studied at the Cincinnati Children's Hospital Medical Center (CCHMC) and in Cleveland …

prednisone
tofacitinib
leflunomide
lupus
  • 72 views
  • 30 Jan, 2022
  • 2 locations