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Found 5 clinical trials
Combination Miltefosine Monotherapy & Antimonial Therapy for Cutaneous Leishmaniasis in New World

treatments comprising meglumine antimoniate for 3 weeks or miltefosine monotherapy for 4 weeks, for the treatment of uncomplicated cutaneous leishmaniasis cases in the New World.

  • 0 views
  • 04 Nov, 2021
  • 5 locations
A Study to Assess the Safety, Efficacy and Immunogenicity of Leishmania Vaccine ChAd63-KH in PKDL

This trial is designed to assess the therapeutic efficacy and safety of CHAd63-KH, a new candidate Leishmania vaccine, in patients with persistent PKDL. 100 participants will be randomly assigned (50 participants in each arm) to receive placebo or ChAd63-KH 7.5 x10(10)vp. Doses will be administered at a single time point.

hepatitis
smear
  • 0 views
  • 21 Mar, 2022
  • 1 location
A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand Flies (LEISHChallenge)

leishmaniasis which can affect the skin (cutaneous leishmaniasis) or the internal organs of the body (visceral leishmaniasis). Some of the milder forms will produce skin problems which will be localised, whilst

Accepts healthy volunteers
  • 0 views
  • 22 Mar, 2022
  • 1 location
Spatial Analysis of Host-parasite Interactions in Cutaneous Leishmaniasis in Ethiopia (SpatialCL)

Cutaneous leishmaniasis manifestations range from self-healing localized skin ulcers/nodules to diffusely spread chronic lesions. Knowledge on the host-parasite interactions underpinning the

  • 0 views
  • 29 Apr, 2022
  • 1 location
Diagnosis and Treatment of Leishmania Infections

and a biopsy to confirm leishmanial infection. The biopsy procedure will be determined by the type of infection local cutaneous leishmaniasis (LCL), mucocutaneous leishmaniasis (MCL) or visceral

blood tests
cutaneous leishmaniasis
punch biopsy
itraconazole
pentostam
  • 21 views
  • 01 Jul, 2022
  • 1 location