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Found 37 clinical trials
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An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

An Open Label Study to Assess the Safety and Efficacy of COR-003 (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

  • 780 views
  • 25 Mar, 2021
  • 30 locations
Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

This phase 2 multicenter, open-label clinical trial will evaluate safety and efficacy of 4 weeks of oral seliciclib in patients with newly diagnosed, persistent, or recurrent Cushing disease

hypercortisolism
progesterone receptor
ketoconazole
mifepristone
pasireotide
  • 8 views
  • 02 May, 2021
  • 1 location
Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome

patients do not have clinical signs of classical Cushing's syndrome, they have an increased risk for hypertension, dyslipidemia, diabetes mellitus, osteoporosis and obesity. The hypothesis of the

  • 2 views
  • 24 Jan, 2021
  • 8 locations
Effects of Mindfulness Therapy in Patients With Acromegaly and Cushing

and then another for patients with Cushing's syndrome.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Hair Cortisol and Cushing's Disease

The biochemical tools usable to assess the control of hypercortisolism in patients with Cushing's disease receiving medical treatments are debatable. The aim of the study is to compare the

  • 0 views
  • 23 Mar, 2021
  • 7 locations
Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic Scars

Summary: Keloids and hypertrophic scars are benign fibrous growth, differing mainly by overgrowth beyond the initial defect in keloid whereas hypertrophic scar is confined to initial lesion and tends to regress over the years. Keloids and hypertrophic scars mainly lead to cosmetic disfigurement and functional deformity depending on site of …

  • 0 views
  • 31 Mar, 2021
  • 1 location
Intraarticular Opioids Vs Glucocorticosteroids in Gonarthritis

Intraarticular application of opioids versus glucocorticosteroids versus placebo in knee arthritis study goals: assessment of effectiveness and tolerability of locally applied morphine, dexamethasone or placebo in knee arthritis

rheumatic diseases
spondyloarthropathies
arthritis
osteoarthritis
opioid
  • 11 views
  • 07 Nov, 2020
  • 1 location
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome

This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the efficacy, safety and pharmacokinetics (PK) of relacorilant in patients with endogenous Cushing

hypertension
diabetes
relacorilant
  • 113 views
  • 30 Jun, 2021
  • 69 locations
Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas

This is a Phase 3, randomized, double-blind, placebo-controlled study to assess the efficacy, and safety of relacorilant to treat hypercortisolism in patients with cortisol-secreting adrenal

hypercortisolism
hyperplasia
adenoma
adrenal adenoma
corticotropin
  • 0 views
  • 12 Jul, 2021
  • 46 locations
Roll-over Study in Patients With Endogenous Cushing's Syndrome for LCI699

The purpose of this study is the evaluation of long-term safety of osilodrostat in patients who have already received osilodrostat treatment in a previous Global Novartis-sponsored trial and who, based on investigators' judgement, will continue benefiting with its administration.

lci699
  • 12 views
  • 26 Jan, 2021
  • 49 locations