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Found 28 clinical trials
Collecting Information About Treatment Results for Patients With Cushing's Syndrome

The purpose of this study is to follow participants with Cushing's syndrome during the course of their routine care and to form a data registry to study long term participant outcomes.

urinary free cortisol
corticotropin
ACTH
adrenal neoplasm
depression
  • 89 views
  • 26 Mar, 2022
  • 7 locations
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome

This is a prospective, multi-center, case-control study where neurocognitive function will be evaluated in 36 patients with Cushing syndrome (CS) and 36 controls matched for age, gender and

adrenal adenoma
corticotropin
Accepts healthy volunteers
adenoma
fatigue
  • 119 views
  • 24 Feb, 2022
  • 1 location
Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to …

  • 0 views
  • 18 Jun, 2021
  • 1 location
Postmortem Evaluation of Adrenal and Other Endocrine Tumors in Patients With Sudden Death (SuddenDeath)

Sudden Cardiac Death is a leading cause of mortality and remains a major public health burden worldwide. Cardiac arrest due to coronary heart disease explains a large proportion of the cases, but if autopsy is not performed the exact underlying cause remains obscure in many adults who face sudden death …

adrenal pheochromocytoma
adrenaline
  • 0 views
  • 04 Oct, 2022
  • 1 location
Cushing's Osteoporosis Specificities (SOCS)

corticosteroids, affecting among 1% of population. In contrast, very few data on osteoporosis are available in the Cushing syndrome (CS), a rare disease affecting 1 or 2 million of inhabitants, and characterized

Accepts healthy volunteers
  • 4 views
  • 25 Feb, 2022
  • 1 location
Adrenal Tumors - Pathogenesis and Therapy

The pathogenesis of adrenal tumors is still not fully elucidated and the treatment options for malignant tumors are poor. The current study investigates different aspects of the pathogenesis of adrenal tumors and evaluates different therapeutic options in patients with adrenocortical carcinoma.

carcinoma
adrenocortical carcinoma
cancer
adrenaline
adrenal neoplasm
  • 60 views
  • 23 Jan, 2022
  • 1 location
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H) (CREST-H)

We aim to determine whether cognitive impairment attributable to cerebral hemodynamic impairment in patients with high-grade asymptomatic carotid artery stenosis is reversible with restoration of flow. To accomplish this aim CREST-H will add on to the NINDS-sponsored CREST-2 trial (parallel, outcome-blinded Phase 3 clinical trials for patients with asymptomatic high-grade …

stroke
carotid artery stenosis
carotid revascularization
cognitive decline
stenosis
  • 36 views
  • 15 Jul, 2022
  • 54 locations
Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study

This is a single center, prospective, observational study to explore and evaluate the differences on cognitive function and brain function by functional-MRI in autonomous cortisol secretion patients, and the different treatments methods on the cognitive function and brain function in patients with autonomous cortisol secretion

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location