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Found 28 clinical trials
Testosterone in Bariatric Patients

Bariatric surgery is an effective method in the treatment of severe obesity and type 2 diabetes mellitus achieving high remission rates. However, weight loss also causes loss of skeletal muscle and bone mass which at least partly could be prevented by exercise and dietary intervention although the counselling of obese …

  • 04 Oct, 2022
  • 1 location
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People (Choko-AGE)

We hypothesize that the antioxidant and cytoprotective functions of vitamin E combined with the cortisol-lowering effect of chocolate polyphenols and physical activity may help prevent the age-dependent decline of mitochondrial function and nutrient metabolism in skeletal muscle, key underpinning events in protein-energy malnutrition (PEM) and muscle wasting in the elderly. …

mental state examination
cognitive impairment
vitamin e
mild cognitive impairment
mild dementia
  • 25 May, 2022
  • 1 location
Long-Term Follow-UP of Survivors of Pediatric Cushing Disease

causes Cushing disease. This disease causes many problems. Some of these problems might persist after the disease is cured. Objective To find out the long-term

urinary free cortisol
dxa scan
Accepts healthy volunteers
cushing's syndrome
stimulation test
  • 27 Oct, 2022
  • 1 location
Effect of Intensive Re-nutrition on Eating Disorder Psychopathology, Cognitive Functions, Anxiety, Depression, and Cortisol Level in Severe Anorexia Nervosa (RESAN)

In anorexia nervosa (AN) it still remains to be clarified, which psychiatric symptoms are the direct consequence of malnutrition and adaptation to starvation and which are not. There is clinical consensus that depression/anxiety and cognitive impairments in AN mainly are sequelae to the malnutrition. However, this consensus is largely based …

  • 11 Oct, 2022
  • 2 locations
Observational Registry on Patients With Endogenous CS to Document Safety and Effectiveness of Ketoconazole. (KetoPASS)

This is a non-interventional, prospective, multinational, multicentre, observational study, in which data collected are those derived from routine clinical practice via an European registry on CS: ERCUSYN.

  • 07 Oct, 2022
  • 6 locations
China Adrenal Disease Registry (CASE)

Epidemiologic studies have revealed a tremendous increase in the prevalence of adrenal associated disease and related mortality worldwide. In order to meet all the therapeutic challenges in adrenal disease in China, CASE was founded in 2020. The objective of CASE is to launch an adrenal disease management model based on …

adrenal pheochromocytoma
  • 23 Mar, 2022
A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related Disorders

of cortisol secretion in pediatric patients with Cushing disease. Continuation of this protocol will eventually lead to new, separate protocols that will address all aspects of diagnosis of

cushing's syndrome
linkage analysis
Accepts healthy volunteers
central nervous system tumors
  • 20 Oct, 2022
  • 1 location
Glucocorticoid Withdrawal Syndrome in Patients With Treated Cushing Syndrome

Cushing syndrome (CS) is an endocrine disorder caused by chronic exposure to glucocorticoid (GC) excess. Endogenous CS has an estimated incidence of 0.2 to 5.0 cases per million per year and

  • 02 Nov, 2021
  • 1 location
Effects of Metyrapone in Patients With Hypercortisolism (CEM)

The aims of the present study are to evaluate in patients with mild hypercortisolism the effect of metyrapone treatment on glycometabolic control, blood pressure, thrombotic risk parameters

  • 06 Jun, 2022
  • 1 location
Evaluation of New Diagnostic Indicator of Subclinical Hypercortisolism

The purpose of this study is to evaluate the serum dehydroepiandrosterone sulfate in subclinical hypercortisolism

Accepts healthy volunteers
  • 02 May, 2022
  • 1 location