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Found 42 clinical trials
Value of Geriatric Screening to Predict Postoperative Morbidity for Head and Neck Cancer (GEROP)

or older. Objectives The investigators aim to determine the value of G8 to predict 30-day postoperative comorbidity in an older HNCA population undergoing elective curative surgery. Moreover

  • 9 views
  • 11 Mar, 2022
  • 1 location
Comparative Efficacy of Cemiplimab to Historical Standard of Care in France (TOSCA)

locally advanced cutaneous Squamous Cell Carcinoma (CSCC) who are not candidates for curative surgery or curative radiation, on overall survival (OS). Secondary Objectives: Assess

  • 0 views
  • 13 Jun, 2022
  • 1 location
Sentinel™ Trial: A Prospective Study Evaluating the Performance and Clinical Benefit of Personalized ctDNA-based MRD Testing to Detect Recurrence and Monitor Treatment Response in Patients With Solid Tumors (Sentinel)

The Sentinel™ Trial is a non-randomized, large-scale observational trial designed to: 1) evaluate the ability of circulating tumor DNA (ctDNA)-based minimal residual disease (MRD) testing to detect recurrence in advance of standard-of-care techniques across solid tumors, and 2) determine the clinical benefit of therapy in ctDNA-positive participants. The study offers …

solid tumor
  • 0 views
  • 14 Jul, 2022
  • 2 locations
Post-authorization Safety Study on the Long Term Safety of Sonidegib in Patients With Locally Advanced Cell Carcinoma (NISSO)

Collect real world safety data on the use of sonidegib in adult patients with laBCC. Document major safety parameters such as on treatment deaths, adverse events (AEs)/ serious adverse events (SAEs) and discontinuation secondary to AEs.

sonidegib 200 mg
carcinoma
sonidegib
  • 2 views
  • 25 Mar, 2022
  • 45 locations
Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer (TRACC)

This is a multi-centre, prospective, translational research study involving the collection and analysis of tumour tissue, serial blood samples and clinical data in patients with newly diagnosed stage I, II and III CRC. The study will also include collection and analysis of tissue, serial blood samples and clinical data of …

metastasis
carcinoma
  • 0 views
  • 14 Feb, 2022
A Stool DNA-based SDC2 Methylation Test for the Early Detection of Colorectal Cancer

The primary objective of this clinical trial is to determine the sensitivity and specificity of the EarlyTect® CRC test for detecting CRC, using colonoscopy as the reference method. The secondary objective is to compare the clinical performance of EarlyTect® CRC test with a commercially available Fecal Immunochemical Test (FIT), with …

  • 0 views
  • 08 Mar, 2022
  • 1 location
Glucocorticoid Withdrawal Syndrome in Patients With Treated Cushing Syndrome

prevalence of 39 to 79 cases per million in various populations. CS usually affects young women, with a median age at diagnosis of 41.4 with a female-to-male ratio of 3:1. Following a curative surgery for CS

  • 0 views
  • 02 Nov, 2021
  • 1 location
Clinical Value of MRD Monitoring for Adjuvant Therapy in Postoperative NSCLC

This clinical trial aims to explore the minimal residual disease (MRD) status of early NSCLC after curative surgery and the clinical outcomes of adjuvant chemotherapy. Next-generation sequencing

cancer chemotherapy
adjuvant chemotherapy
  • 0 views
  • 01 Jan, 2022
  • 1 location
Resection of the Esophagus and Subsequent Weight Loss

The investigators aim to ascertain how food reward signals and eating behaviour relates to the gut-brain pathway in weight-losing patients after curative surgery for oesophageal cancer, and how

  • 0 views
  • 23 Feb, 2021
  • 1 location
The Registry of Genetic Alterations of Taiwan Biliary Tract Cancer

Biliary tract cancer (BTC) compromises a heterogenous group of tumors with poor prognoses. Curative surgery remains the first choice for localized disease; however, most BTC patients had

  • 0 views
  • 03 Jul, 2022
  • 6 locations