Found 46 clinical trials
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For females only
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Family Medicine
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Currently Recruiting
Phase 2 Trial of Neoadjuvant Weekly Carboplatin Plus Paclitaxel in Triple Negative Breast Cancer
Nonrandomized, open label, single arm study of neoadjuvant weekly carboplatin plus paclitaxel, followed by doxorubicin and cyclophosphamide in patients with operable Triple Negative Breast Cancer (TNBC)
- 54 views
- 23 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Low-dose Y90 Treatment Planning for HCC
The study proposes low-dose Y90 microspheres for therapy planning of HCC, as an alternative to Technetium (99mTc) albumin aggregated (MAA), to be a bioidentical therapeutic Y90 surrogate marker to better predict and thus achieve optimal therapeutic dosing.
- 0 views
- 25 Jan, 2021
- 3 locations
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma
Primary Objective: To confirm the safety and feasibility of canakinumab and spartalizumab (PDR-001) administered using a standard dose / schedule in the neo-adjuvant setting in renal cell carcinoma Secondary Objectives: To assess the immune response to combination canakinumab and spartalizumab To assess anti-tumor activity as measured by pathologic downstaging
- 1 views
- 29 Jan, 2021
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Family Medicine
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Currently Recruiting
Prostate Cancer - Patient Empowerment Program
Each year over 20,000 men are diagnosed with prostate cancer in Canada with the majority undergoing some form of treatment option. Radical prostatectomy and/or radiation therapy are common procedures that are effective in the treatment of prostate cancer. However, they typically incur both short- and long-term side effects (e.g. urinary …
- 5 views
- 04 Feb, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Calcium Channel Blockade in Primary Aldosteronism
Primary aldosteronism is a common cause of hypertension. Recent evidence suggests that many patients with bilateral idiopathic hyperaldosteronism harbor gain-of-function somatic mutations in zona glomerulosa calcium channels that results in aldosterone production. This finding raises the possibility that calcium channel antagonists may be a targeted therapy to reduce aldosterone production …
- 0 views
- 25 Jan, 2021
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Currently Recruiting
International Low Anterior Resection Score Evaluation
using the LARS score. Primary outcome measure: LARS score before surgery and 1 year after the surgery. Primary comparison: Between average LARS score before and after curative
- 2 views
- 23 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An observational study
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For all genders
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Currently Recruiting
Value of Geriatric Screening to Predict Postoperative Morbidity for Head and Neck Cancer
or older. Objectives The investigators aim to determine the value of G8 to predict 30-day postoperative comorbidity in an older HNCA population undergoing elective curative surgery. Moreover
- 9 views
- 29 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Currently Recruiting
CPET and Outcome After Oesophagogastric Cancer Surgery
surgery. Patients undergoing neoadjuvant chemotherapy or chemoradiotherapies will also be included. Patients having a CPET and initially scheduled for curative surgery, but end up not having surgery due
- 0 views
- 26 Jan, 2021
- 1 location
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An observational study
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For all genders
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Oncology
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Currently Recruiting
Evaluation of PET and Laparoscopy in STagIng Advanced Gastric Cancer
of gastric cancer, as staging modalities for advanced (T3-4) tumors after initial staging. The costs of the study population will be compared to retrospective data of patients who underwent curative
- 3 views
- 21 Jan, 2021
- 1 location
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Multi-country trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An observational study
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For all genders
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Currently Recruiting
Post-authorization Safety Study on the Long Term Safety of Sonidegib in Patients With Locally Advanced Cell Carcinoma
Collect real world safety data on the use of sonidegib in adult patients with laBCC. Document major safety parameters such as on treatment deaths, adverse events (AEs)/ serious adverse events (SAEs) and discontinuation secondary to AEs.
- 2 views
- 28 Jan, 2021
- 35 locations