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Found 43 clinical trials
PIPAC for Peritoneal Metastases

not amenable to curative surgery. This study is to determine safety and feasibility of PIPAC in patients with PM from Gastrointestinal (GI) cancer, Hepato-Pancreato-Biliary (HPB) cancer, and other

  • 0 views
  • 29 Dec, 2021
  • 1 location
Preoperative CRT With Capecitabine Temozolomide in Patients With LARC

This is a prospective biomarker-stratified, randomised phase II study of preoperative CRT with temozolomide plus capecitabine in patients with locally advanced rectal cancer. The primary endpoint is pathologic complete response rates defined as total regression of the primary tumor. For each cohort of MGMT hypermethylated versus MGMT unmethylated, patients will …

  • 26 views
  • 27 Jan, 2021
  • 1 location
PREACT Study: Locally Advanced Gastric Cancer, Chemoradiotherapy vs. Chemotherapy Followed by D2 Surgery and Adjuvant Chemotherapy (PREACT)

very poor. Although the Magic trial showed that perioperative chemotherapy can increase the rate of curative surgery and significantly improve overall survival in patients with operable gastric or

curative surgery
immunomodulator
adjuvant chemotherapy
chemoradiotherapy
gastric adenocarcinoma
  • 22 views
  • 24 Feb, 2022
  • 1 location
Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers

BACKGROUND In patients with high risk stage II and stage III colon cancer (CC), curative surgery followed by adjuvant chemotherapy with FOLFOX or CAPOX regimens

  • 0 views
  • 23 Mar, 2022
  • 1 location
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

The performance of SGM-101, an intraoperative imaging agent, will be compared to that of standard "white light" visualization during surgical resections of colorectal cancer.

cancer surgery
metastasis
rectal carcinoma
  • 4 views
  • 11 May, 2022
  • 8 locations
Comprehensive Care Program for Their Return to Normal Life Among Lung Cancer Survivors

The purpose of this study is to develop a comprehensive care program for their return to normal life and community among lung cancer survivors and evaluate the effectiveness of the program.

cancer
lung cancer
lung carcinoma
  • 0 views
  • 21 Oct, 2021
  • 1 location
Perioperative Intervention to Reduce Metastatic Processes in Pancreatic Cancer Patients Undergoing Curative Surgery (BC-PC)

In Israel, of the ~1000 patients diagnosed annually with pancreatic cancer (PC), approximately 250 (25 percent) will be eligible for curative surgery, of which 80 percent will succumb to post

adenocarcinoma
metastasis
  • 9 views
  • 18 Feb, 2022
  • 2 locations
P1101 and Anti-PD1 for After Curative Surgery of Hepatitis B-related Hepatocellular Carcinoma

The main purpose of this trial is to evaluate the safety of the new adjuvant treatment of curative HCC, or the treatment of long-acting interferon P1101 alone, or the use of long-acting interferon P1101 and subsequent treatment of anti-PD1, and any efficacy in reducing the recurrence rate of patients after …

nivolumab
interferon
hepatitis b surface antigen
hepatitis
  • 1 views
  • 23 Mar, 2022
  • 1 location
A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy

This study will look at the recurrence-free survival of microsatellite-stable (MSS) colon cancer in patients are ctDNA (circulating tumor DNA) positive and treated with gevokizumab.

  • 0 views
  • 12 Aug, 2022
  • 3 locations
Thromboprophylaxis in Oesophageal Cancer Patients

The purpose of the study is to examine the efficacy and safety of prolonged thromboprophylactic treatment with Fragmin in oesophageal cancer patients undergoing intended curative surgery.

cancer
esophagus cancer
  • 0 views
  • 10 Oct, 2021
  • 1 location