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Found 678 clinical trials
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IS Metomidate PET-CT Superior to Adrenal Venous Sampling in Predicting Outcome From Adrenalectomy in Patients With Primary Hyperaldosteronism

Purpose of this clinical trial is to improve prediction of outcomes from surgical intervention in patients with Primary aldosteronism, and evaluate the merits of non-invasive metomidate PET CT versus adrenal vein sampling in the diagnosis of surgically correctable aldosteronism.

adrenal adenoma
lisinopril
adrenalectomy
renin
adrenal venous sampling
  • 4 views
  • 28 Jan, 2021
  • 1 location
None
Swiss SOS MoCA - DCI Study

The primary objective of this multicenter observational study is to determine the effect size of the relationship between DCI and neuropsychological impairment 14-28 days and 3 months after aSAH. Secondary objectives are the feasibility to administer and the validity of the MoCA in an intensive care unit setting, as well …

hydrocephalus
coma
traumatic brain injury
aneurysm
stroke
  • 34 views
  • 26 Jan, 2021
  • 10 locations
None
Serological Testing for COVID-19 (SARS-CoV-2) in ESKD

Starting in late 2019, the world is facing a pandemic with the SARS-CoV-2 virus. Patients with end-stage kidney disease and on treatment with renal replacement therapy are high risk patients, as they are unable to maximize social distancing. We plan to gather epidemiological data using two different diagnostic approaches. We …

nasopharyngeal swab
SARS
chronic renal failure
renal disease
computed tomography
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Use of Thoracoscopic Intraoperative Lung Ultrasound to Identify Pulmonary Metastases in Patients Submitted to Pulmonary Metastasectomy With Radical Intent.

Experience drawn from many scientific articles showed that many patients who develop a limited pattern of pulmonary metastases after treatment of a primary tumor may benefit from surgical resection of the lung deposits. Pulmonary metastasectomy with curative intent is widely performed with the aim of prolonging life and, in some …

metastasectomy
primary tumor
ct scan
vats
  • 0 views
  • 25 Jan, 2021
  • 1 location
None
The Potential of Patient-reported Outcome Measures in Detection of Relapse in Diffuse Large B-cell Lymphoma

Annually some 450 patients are diagnosed with Diffuse Large B-cell Lymphoma (DLBCL), in Denmark. The majority of these patients are cured with immunochemotherapy, but up to 30 % will relapse, pointing to the need for targeted surveillance and follow-up strategy. However, this strategy is constantly under debate illustrated by the …

  • 0 views
  • 18 Feb, 2021
  • 1 location
None
Clinical Outcome Study of Minimally Invasive Decompression for Lumbar Spinal Stenosis

The study is a prospective outcome study to evaluate the effectiveness and treatment outcomes of microendoscopic decompressive laminotomy (MEDL) with objective evaluation tools. The patients who fulfill the selection criteria will be enrolled to collect the pre-operative clinical data including demographic data, image studies, and functional evaluation for neurological symptoms …

ct scan
conservative management
leg pain
intermittent claudication
  • 2 views
  • 07 Nov, 2020
  • 1 location
None
Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography

The long-term goal of this project is to utilize very high-speed optical coherence tomography (OCT) technology to guide surgical treatments of corneal diseases. OCT is well known for its exquisite resolution, but until recently it has not had sufficient speed to capture the shape of the cornea because of eye …

myopia
refractive surgery
intraocular lens implantation
  • 101 views
  • 23 Jul, 2021
  • 1 location
None
Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction

An incisional hernia is technically challenging to operate and is the most frequent long-term complication after open surgery, resulting in impaired quality of life and reduced physical ability. Large hernias contain large amounts of abdominal volume, which similarly are missing from the abdominal cavity. Due to adaptations of the abdominal …

renal injury
blood tests
incisional hernia repair
open surgery
tension
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
BEAM: Brain-Eye Amyloid Memory Study

The main objectives for this study are: To investigate novel, non-invasive ocular measurements including optical coherence tomography and eye tracking in a cross-sectional study of participants with various neurodegenerative dementias against standard cognitive assessments and brain imaging measures; and To assess the potential utility of ocular assessments for early detection …

alzheimer's disease
brain imaging
cytokines
mental state examination
apolipoprotein e
  • 28 views
  • 01 Oct, 2021
  • 5 locations
None
Covid-19: Possible Role of Neutrophil Extracellular Traps

The process by which neutrophils expel DNA together with various proteins to the outside, forming a network structure called Neutrophil Extracellular Traps (NETs) constitutes a particular cell death that involves the destruction of the nuclear membrane before the plasmatic one. This process is called NETosis and differs from other known …

cytokines
covid-19
hypercytokinemia
cytokine storm
interferon
  • 0 views
  • 24 Jan, 2021
  • 1 location