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Found 310 clinical trials
Featured trial
CT COMPARE: CT COronary Angiography to Measure PlAque REduction

The study is investigating how the amount of plaque in your arteries can be reduced by statin medication. Researchers at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland, are looking for volunteers to participate in a 36-month study. There are no costs for study-related tests, procedures or medication. For …

statin therapy
hyperlipidemia
hmg-coa reductase inhibitors
  • 365 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma(CLL/SLL), Lymphoplasmacytic Lymphoma(LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma(SMZL)

Background: The development of new technologies now allow scientists to investigate the molecular basis and clinical manifestations of monoclonal B cell lymphocytosis (MBL), chronic lymphocytic leukemia(CLL)/small lymphocytic lymphoma (SLL), lymphoplasmacytic lymphoma (LPL)/Waldenstrom macroglobulinemia (WM), and splenic marginal zone lymphoma (SMZL). Applying these methods in a natural history study can clarify …

waldenstrom's macroglobulinemia
chronic lymphocytic leukemia
cancer
lymphoma
marginal zone lymphoma
  • 115 views
  • 15 Apr, 2019
  • 1 location
Featured trial
A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

  • 588 views
  • 07 Nov, 2020
  • 1 location
Featured trial
A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the effect of secukinumab on aortic vascular inflammation and cardiometabolic biomarkers after 12 weeks of treatment, compared to placebo, and up to 52 weeks of treatment with secukinumab in adult subjects with moderate to severe chronic plaque-type psoriasis

A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the effect of secukinumab on aortic vascular inflammation and cardiometabolic biomarkers after 12 weeks of treatment, compared to placebo, and up to 52 weeks of treatment with secukinumab in adult subjects with moderate to severe chronic plaque-type psoriasis

  • 384 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Phase I Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib in Children with Refractory Solid Tumors or Refractory Leukemias

Phase I Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib in Children with Refractory Solid Tumors or Refractory Leukemias

  • 6 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

  • 229 views
  • 25 Mar, 2021
  • 1 location
Lung Cancer Screening With Low-dose CT Scan in Women : Implementation Study (CASCADE)

The purpose of this study is to determine whether reading of low-dose thoracic CT scans can be done by a single general radiologist who has been trained to lung cancer screening, and will

  • 0 views
  • 16 Oct, 2022
  • 1 location
PSMA-PET Registry for Recurrent Prostate Cancer (PREP)

This study aims to institute a province-wide registry leveraging the availability of a new Positron Emission Tomography tracer, [18F]-DCFPyL and PET expertise across Ontario centers to improve our ability to characterize patterns of recurrence and personalize therapies in men with recurrent prostate cancer after primary treatment.

prostatectomy
ct scan
positron emission tomography
bone scan
karnofsky performance status
  • 108 views
  • 15 Feb, 2022
  • 6 locations
Assessment of the Benefit of an Inclusive Health Organization on the Prognosis of Severe Trauma Patients (TRAUMINXCLUSIF)

Appropriate management reduces the mortality of severe trauma victims. This is based on a pre-hospital medical assessment of severity, the initiation of life-saving treatments at the pre-hospital level, and referral to a hospital with human and material resources adapted to the patient's severity. The objective of this research project is …

  • 0 views
  • 20 Jun, 2022
  • 1 location
Lobectomy for NSCLC by VATS Versus Thoracotomy

The goal of this study is to determine video-assisted thoracoscopic surgery is non-inferior to thoracotomy in terms of disease-free survival for solid clinical stage T1N0M0 NSCLC.

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location