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Found 328 clinical trials
Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to explore the effect of oral ozanimod as an induction treatment for subjects with moderately to severely active Crohn's

crohn's disease
ileal disease
endoscopy
corticosteroids
immunomodulators
  • 865 views
  • 09 Mar, 2021
  • 421 locations
Ileal Crohn's Disease and Post-operative Outcome: Prospective Cohort Study of the REMIND Group

Crohn's disease (CD), a chronic inflammatory process in intestinal segments leads to tissue damage. More than two thirds of CD patients need intestinal resection. Symptomatic clinical recurrence

crohn's disease
bowel resection
tumour necrosis
tumor necrosis factor
thiopurines
  • 9 views
  • 27 Mar, 2021
  • 17 locations
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is a Phase 3, open-label, multicenter extension study to evaluate safety and efficacy of ozanimod in subjects with moderately to severely active Crohn's Disease.

crohn's disease
remission
  • 1037 views
  • 22 Feb, 2021
  • 808 locations
Diet for Induction and Maintenance of Remission and Re-biosis in Crohn's Disease

The modified-Exclusive Enteral Nutrition (mEEN) is an open label randomized controlled trial in mild to severe Crohn's Disease patients. The purpose of this study is to determine whether

crohn's disease
enteral nutrition
induction of remission
remission
  • 497 views
  • 26 Jan, 2021
  • 10 locations
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

The reason for this study is to determine the long-term efficacy and safety of the study drug mirikizumab in participants with Crohn's disease.

crohn's disease
  • 22 views
  • 22 Sep, 2021
  • 335 locations
A Study Testing How BI 655130 Works in Patients With Fistulizing Crohn's Disease

This is a study in adults with Crohn's Disease who also have fistulas near the anus. The study has 2 parts. The first part is to find out more about what causes the fistulas. In this part of the

crohn's disease
tumor necrosis factor alpha
stem cell transplantation
prednisone
biosimilar
  • 13 views
  • 22 Sep, 2021
  • 19 locations
A Study Evaluating Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the efficacy of JNJ-active as measured by the change in the Crohn's Disease Activity Index (CDAI) score and Simplified Endoscopic Score for Crohn's

crohn's disease
prednisone
corticosteroids
immunomodulators
mercaptopurine
  • 84 views
  • 07 Sep, 2021
  • 157 locations
Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD)

Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. This study will evaluate how well risankizumab works compared to ustekinumab. This

crohn's disease
tumour necrosis
tumor necrosis factor
risankizumab
ustekinumab
  • 97 views
  • 22 Sep, 2021
  • 484 locations
Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

The primary objectives of this study are to evaluate the safety and efficacy of filgotinib during induction and maintenance treatment of moderately to severely active Crohn's disease (CD) in

crohn's disease
vedolizumab
tumor necrosis factor alpha
remission
tumour necrosis
  • 12 views
  • 04 Jul, 2021
  • 552 locations
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease

crohn's disease
ileocolitis
endoscopy
fistulising crohn's disease
ileitis
  • 794 views
  • 07 Sep, 2021
  • 807 locations