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Found 323 clinical trials
A Study of Darvadstrocel in Adults With Crohn's Disease and Complex Perianal Fistula (EMPIRE)

The main aim is to check the long term side effects of a repeat treatment of darvadstrocel and to see if that treatment improves symptoms of Crohn's disease and complex perianal fistula

crohn's disease
remission
  • 0 views
  • 06 Mar, 2022
  • 27 locations
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is an extension study to evaluate safety and efficacy of ozanimod in participants with moderately to severely active Crohn's Disease.

crohn's disease
remission
  • 1128 views
  • 28 Jul, 2022
  • 482 locations
Ileal Crohn's Disease and Post-operative Outcome: Prospective Cohort Study of the REMIND Group (POP-REMIND)

Crohn's disease (CD), a chronic inflammatory process in intestinal segments leads to tissue damage. More than two thirds of CD patients need intestinal resection. Symptomatic clinical recurrence

thiopurines
crohn's disease
microbiota
mercaptopurine
bowel resection
  • 9 views
  • 27 Feb, 2022
  • 12 locations
A Study to Test Whether BI 706321 Combined With Ustekinumab Helps People With Crohn's Disease

This study is open to adults, aged 18-75 years, with moderate to severe Crohn's disease. The purpose of this study is to find out whether BI 706321 combined with ustekinumab helps people

faecal calprotectin
corticosteroids
methotrexate
tumour necrosis
endoscopy
  • 1 views
  • 10 Aug, 2022
  • 31 locations
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe Crohn's disease will be treated with

pediatric onset crohn's disease
colitis
vedolizumab
azathioprine
enteral nutrition
  • 0 views
  • 13 Jun, 2022
  • 41 locations
A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease (GRAVITI)

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with Crohn's disease.

crohn's disease
abdominal pain
  • 0 views
  • 24 Jul, 2022
  • 11 locations
An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's Disease

The purpose of this study is to assess the safety and effectiveness of BMS-986165 compared to placebo in participants with moderately to severely active Crohn's Disease.

enteropathy
crohn's disease
  • 372 views
  • 11 Jul, 2022
  • 216 locations
Effect of Ileocolonic Delivered Vitamins and an Anti-Inflammatory Diet on Crohn's Disease and Healthy Volunteers (Vita-GrAID)

This study will evaluate if the Groningen Anti-Inflammatory Diet and the ileocolonic delivery of vitamin B2, B3 and C can positively influence the course of Crohn's disease and can positively

faecal calprotectin
Accepts healthy volunteers
mucosal inflammation
vitamin
crohn's disease
  • 0 views
  • 11 Aug, 2022
  • 1 location
A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn's Disease

A perianal fistula is an abnormal passageway that develops between the rectum and the skin near the anus. The fistula is considered complex if it branches into several openings or an abscess is also present. The main aim of this study is to learn if complex perianal fistulas in children …

corticosteroids
methotrexate
mercaptopurine
monoclonal antibodies
luminal
  • 0 views
  • 27 Oct, 2021
  • 23 locations
Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

corticosteroids
ileal disease
endoscopy
crohn's disease
immunomodulators
  • 550 views
  • 22 Jul, 2022
  • 354 locations