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Found 331 clinical trials
A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease (VIVID-1)

The reason for this study is to see if the study drug mirikizumab is safe and effective in participants with moderately to severely active Crohn's disease.

crohn's disease
ustekinumab
  • 728 views
  • 23 Jul, 2022
  • 563 locations
Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis

Crohn's disease. Vedolizumab, a novel biologic agent, is a recombinant humanized monoclonal antibody that specifically antagonizes intestine-selective α4β7 integrins on the surface of leukocyte subsets

Accepts healthy volunteers
  • 0 views
  • 09 Aug, 2022
  • 1 location
Ileal Crohn's Disease and Post-operative Outcome: Prospective Cohort Study of the REMIND Group (POP-REMIND)

Crohn's disease (CD), a chronic inflammatory process in intestinal segments leads to tissue damage. More than two thirds of CD patients need intestinal resection. Symptomatic clinical recurrence

tumour necrosis
microbiota
luminal
mercaptopurine
crohn's disease
  • 9 views
  • 27 Feb, 2022
  • 12 locations
A Study of Darvadstrocel in Adults With Crohn's Disease and Complex Perianal Fistula (EMPIRE)

The main aim is to check the long term side effects of a repeat treatment of darvadstrocel and to see if that treatment improves symptoms of Crohn's disease and complex perianal fistula

crohn's disease
remission
  • 0 views
  • 06 Mar, 2022
  • 27 locations
A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn's Disease

A perianal fistula is an abnormal passageway that develops between the rectum and the skin near the anus. The fistula is considered complex if it branches into several openings or an abscess is also present. The main aim of this study is to learn if complex perianal fistulas in children …

azathioprine
luminal
mercaptopurine
ulceration
crohn's disease
  • 0 views
  • 27 Oct, 2021
  • 23 locations
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe Crohn's disease will be treated with

  • 0 views
  • 13 Jun, 2022
  • 40 locations
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease (UNITI Jr)

ustekinumab exposure (pharmacokinetics [PK]) in pediatric participants with moderately to severely active Crohn's disease.

ustekinumab
fistulising crohn's disease
colitis
ileitis
ulceration
  • 0 views
  • 07 Jul, 2022
  • 42 locations
An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's Disease

The purpose of this study is to assess the safety and effectiveness of BMS-986165 compared to placebo in participants with moderately to severely active Crohn's Disease.

crohn's disease
enteropathy
  • 372 views
  • 11 Jul, 2022
  • 216 locations
Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

crohn's disease
abdominal pain
endoscopy
immunomodulators
ileal disease
  • 550 views
  • 22 Jul, 2022
  • 272 locations
A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease (GRAVITI)

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with Crohn's disease.

crohn's disease
abdominal pain
  • 0 views
  • 24 Jul, 2022
  • 11 locations