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Found 281 clinical trials
Analysis of Passive Leg Raise Test on Blood Pressure in Critically Ill Patients.

Positioning intensive care patients in Trendelenburg position to identify fluid responsiveness assessed by PiCCO device.

  • 0 views
  • 12 Oct, 2022
Gastric Content Ultrasound Monitoring Prior to Extubation in Critically Ill Children (GastrExtub)

Nearly half of critically ill children are intubated and enterally fed according to recent guidelines. However, no evidence-based recommendation are available regarding fasting times prior to extubation. When an extubation is planned, children do not always present with normal neurological status yet, and are at risk of vomiting and aspiration. …

  • 0 views
  • 19 Apr, 2022
Exploring the Relationship Between Mitochondrial Health and Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients (MitoHIRRT)

Renal replacement therapy is a life-saving treatment for patients who have sudden and severe kidney failure. However, some of these patients blood pressure who receive this treatment could become unstable, thus resulting in more injuries to their kidneys and may limit the ability of kidney recovery. In order to mitigate …

renal replacement therapy
  • 0 views
  • 19 Oct, 2022
  • 1 location
Incidence of Acute Kidney Injury and Mortality in Critically Ill Patients: Urinary Chloride as a Prognostic Marker

Acute kidney injury (AKI) is characterized by a rapid decrease in renal function. It is frequent in hospitalized patients and its incidence is higher in critically ill patients. It is associated with high rates of morbidity and mortality. AKI affects over 13 million people per year globally, and results in …

  • 0 views
  • 12 Oct, 2022
Posaconazole Prophylaxis for CAPA Prevention in Critically-Ill Patients

COVID-19 associated pulmonary aspergillosis (CAPA) is considered a potentially life-threatening infection in critically ill COVID (Corona Virus disease)-19 patients. This study will investigate the efficacy of mold-active prophylaxis with posaconazole for patients with severe SARS (severe acute respiratory syndrome)-CoV-2 infection admitted to the ICU (intensive care unit) in a multi-center …

posaconazole
bronchopulmonary aspergillosis
  • 0 views
  • 10 Oct, 2021
  • 1 location
Pro-inflammatory Role of Blood Platelets in Critically Ill Patients With Septic Shock.

Blood platelets play a major role in the inflammatory response. A dysregulation of platelets activation may be one of the contributors to tissue damage in critically ill patients with septic shock. The main objective of this study is to compare platelet activation markers levels (including plasma concentration in CD154, beta …

  • 0 views
  • 14 Jun, 2021
  • 2 locations
Mitochondrial Oxygen Measurement Variability in Critically Ill Patients (INOX Variability Study)

To determine the between- and within-subject variability of the mitochondrial oxygenation measurement with the COMET device over time in healthy subjects and in hemodynamically stable subjects admitted to the intensive care unit.

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Risk Factors for Acute Kidney Injury in Critically Ill Patients With Acute-on-Chronic Liver Failure

Acute kidney injury (AKI) is one of the most important factors associated with increased mortality in patients with acute-on-chronic liver failure (AoCLF). Early identification and treatment of this subgroup of patients may improve survival and decrease ICU length of stay. As kidney ischemia is one of the main mechanisms responsible …

  • 0 views
  • 23 Sep, 2021
  • 1 location
Capnodynamic Monitoring of Cardiorespiratory Function in Critically Ill Patients

Capnodynamic monitoring has the potential to offer continuous and non-invasive measurements of heart and lung function in patients requiring ventilation in an intensive care setting. Since mechanical ventilation with full patient synchronization is commonly used in ICU, capnodynamic monitoring can be immediately embedded in clinical care and compared to current …

mechanical ventilation
shock
pneumonia
acute respiratory distress syndrome
septic shock
  • 0 views
  • 27 Oct, 2021
  • 1 location
Observational Trial on Cytokine Adsorption in Sepsis

To determine the specific population of critically ill septic patients who benefit most from cytokine adsorption therapy with the HA-380 cartridge. Benefit of the treatment will be assessed on the basis of: The scope of the effect of cytokine adsorption therapy in this specific population of critically ill patients expressed …

shock
antibiotics
septic shock
cytokines
  • 0 views
  • 30 Sep, 2021
  • 1 location