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Found 58 clinical trials
Administration of Adipose-derived Stem Cells (ASC) in Patient With Critical Limb Ischemia

injected in patients with critical limb ischemia and no option for revascularization, had a very good tolerance and interesting effects on skin oxygenation and healing. The aim of the present

  • 0 views
  • 25 Jan, 2021
  • 2 locations
Polytetrafluoroethylen (PTFE) Vascular Prostheses With Heparin Bonded Luminal Surfaces vs Crude ePTFE (REPLACE)

Open repair could be recommended in a first line of treatment to revascularize critical limb ischemia patients or performed in a second line of treatment in case of failure of endovascular

  • 5 views
  • 13 Feb, 2022
  • 1 location
Coronary Revascularization Versus Conservative Therapy in Patients With Treated Critical Limb Ischemia (INCORPORATE)

artery disease, underwent peripheral artery revascularization due to critical limb ischemia. The INCORPORATE trial is designed to be non-blinded, open-label, prospective 1:1 randomized controlled

  • 1 views
  • 15 Feb, 2022
  • 1 location
LIFE-BTK Randomized Controlled Trial (LIFE-BTK)

Pre-market clinical evaluation of the everolimus eluting Esprit™ BTK System for the planned treatment of narrowed infrapopliteal lesions.

  • 100 views
  • 07 Jun, 2022
  • 54 locations
Swedish Drug-elution Trial in Peripheral Arterial Disease

ischemic ulcers/gangrene (critical limb ischemia), putting the extremity at risk of amputation, to exercise-induced pain (intermittent claudication), limiting the patients daily activities. Invasive

vascular disease
gangrene
intermittent claudication
revascularisation
rest pain
  • 40 views
  • 26 Jan, 2021
  • 1 location
Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism

myocardial infarction, stroke or systemic embolism, critical limb ischemia, or coronary or peripheral ischemia requiring revascularization (major adverse cardiovascular events, including major adverse limb

thrombosis
COPD
anticoagulant therapy
asthma
inflammatory bowel disease
  • 0 views
  • 11 Jul, 2021
  • 1 location
The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM

This trial is a pivotal, placebo-controlled, double-blind, parallel-group, adaptive trial conducted in subjects with DM and CLI Rutherford Category 5. Minimisation will be used to assign eligible subjects in a 2:1 ratio to receive a single intra-arterial administration of REX-001 or matching placebo into the index limb.

revascularisation
estrogen
glycosylated hemoglobin
ischemic ulcer
hemoglobin a1c
  • 36 views
  • 29 Jan, 2022
  • 14 locations
Major Adverse Limb Events in Patients With Femoro-popliteal and Below-the-knee Peripheral Arterial Disease Treated With Either Sirolimus-coated Balloon or Standard Uncoated Balloon Angioplasty

The SirPAD trial is an academic, investigator-initiated, single-center, randomized, non-inferiority, open-label clinical trial investigating whether the use of sirolimus-coated balloon catheters in patients with peripheral artery disease of the femoro-popliteal or below-the-knee segment is not inferior to that of uncoated balloon catheters for major clinical outcomes (unplanned major amputation, target …

sirolimus
balloon angioplasty
  • 3 views
  • 13 Apr, 2022
  • 2 locations
Nutrition in Patient With Critical Limb Ischemia (NutriVasc)

A prospective pilot study examining nutritional supplements among vascular surgery patients with Critical Limb Ischemia (CLI). CLI patients have a high rate of malnutrition and has the potential

limb ischemia
ischemia
  • 4 views
  • 10 May, 2022
  • 1 location
Trial to Assess Chelation Therapy in Critical Limb Ischemia (TACT3a)

TACT3a is a double blind, placebo-controlled, randomized trial to test a novel therapy, edetate disodium-based chelation of environmentally acquired toxic metals, to reduce cardiovascular events including amputation in high-risk diabetic patients.

angiography
fasting
gangrene
rest pain
fasting blood glucose
  • 22 views
  • 09 Feb, 2022
  • 1 location