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Found 293 clinical trials
Alpha 2 Agonists for Sedation to Produce Better Outcomes From Critical Illness (A2B Trial)

Many patients in intensive care (ICU) need help to breathe on a breathing machine and need pain killers and sedatives to keep them comfortable and pain free. However, keeping patients too deeply sedated can make their ICU stay longer, can cause ICU confusion (delirium) and afterwards may cause distressing memories. …

  • 283 views
  • 27 Jan, 2021
  • 29 locations
PROSpect: Prone and Oscillation Pediatric Clinical Trial

supportive practices during their critical illness. The overall objective of this study is to identify the best positional and/or ventilation practice that leads to improved patient outcomes in these

  • 0 views
  • 25 Jan, 2021
  • 42 locations
SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival

Patients suffering lung failure, possibly from COVID-19 or hypoxic lung failure, will need life-saving support from a breathing machine. Any patient needing this support requires drugs to keep them sleepy, or "sedated" to be comfortable on this machine. Sedation is made possible by using drugs given through a vein. Unfortunately, …

critical illness
  • 25 views
  • 26 Jan, 2021
  • 10 locations
COVID-19 Watch + COVID-19 Pulse

The clinical guidance for 90 percent of infected COVID-19 adult patients who do not meet eligibility for inpatient admission is to self-isolate. To support these patients, alternatives to in-person care are needed to manage an unpredictable clinical course; identify and intercept patients rapidly deteriorating at home, prevent viral spread during …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Lithium Dilution Method in Guiding Fluid Therapy in Critically Ill Patients

Hypothesis: Fluid management guided by LiDCO doesn´t increase cumulative fluid balance and shorten organ dysfunction compared to fluid management based on CVP and clinical judgment.

  • 0 views
  • 07 Nov, 2020
  • 1 location
Nutrition and Exercise in Critical Illness

This study proposes a novel early intervention combining Intravenous (IV) amino acids plus in-bed cycle ergometry exercise to improve physical outcomes in critically ill patients. The investigators hypothesize that this innovative approach will improve short-term physical functioning outcomes (primary outcome), as well as amino acid metabolism, body composition, and patient-reported …

critical illness
mechanical ventilation
  • 38 views
  • 22 Jan, 2021
  • 4 locations
Effects of Neuromuscular Electrical Stimulation on Exercise Capacity in Respiratory Critically Ill Patients

Neuromuscular electrical stimulation (NMES) implemented during the intensive care unit(ICU) stay may improve exercise capacity and prevent muscular weakness in critically ill patients with respiratory disease. Main objective: To evaluate, in respiratory critically ill patients, the effects of a conventional physiotherapy program with or without additional NMES applied only during …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Digital Rehabilitation Environment Augmenting Medical System

D.R.E.A.M.S. will assess an immersive digital reality-augmenting system in reducing the occurrence of cognitive, behavioral, and emotional consequences of critical illness and environmental

confusion
critical illness
  • 0 views
  • 26 Jan, 2021
  • 1 location
Early Mobilization in the ICU

To study all ICU patients with an independent baseline functional status , who experience a critical illness requiring intubation and mechanical ventilation evaluating long-term cognitive and

intubation
critical illness
assisted ventilation
mechanical ventilation
  • 15 views
  • 26 Jan, 2021
  • 1 location
Diaphragm Dysfunction During Prolonged Mechanical Ventilation

increases the economic burden of critical illness. Ventilator-dependence results from an imbalance between the load and capacity of the respiratory muscle pump. Patients who fail a trial of spontaneous

  • 0 views
  • 25 Jan, 2021