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Found 158 clinical trials
Comparing TAP Blocks Bupivacaine, and Placebo for Plane (CLEVELAND)

The study will prospectively compare the analgesic efficacy of TAP blocks with liposomal bupivacaine, plain bupivacaine, and placebo in patients who are scheduled for major abdominal surgery. The primary aim is to assess the duration of the local analgesia (determined by pinprick and cold) in all four quadrants. Comparing opioid …

  • 0 views
  • 15 Mar, 2022
  • 1 location
Psychobiological Processes in Social Evaluation

Higher-weight individuals face pervasive weight-related stigma and discrimination in their daily lives. There is conceptual and empirical evidence to suggest that weight stigma contributes to worse physical and psychological health outcomes, mediated by the deleterious psychobiological responses to psychosocial stress. Activating self-soothing emotional states (such as self-compassion) may protect against …

Accepts healthy volunteers
  • 0 views
  • 18 May, 2022
  • 1 location
Metabolic Response Evaluation of Low-sugar Snack Bars

To determine the post-prandial metabolic response and biomarker response, following the consumption of newly developed low glycaemic index (GI) snack bars. The snack bars are formulated with different combinations and ratios of ingredients and food structures. The low sugar products maintaining glucose homeostasis and preventing metabolic problems may have commercial …

fasting
body mass index
sugars
fasting blood glucose
Accepts healthy volunteers
  • 16 views
  • 04 Oct, 2022
  • 1 location
Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy

All three methods of postoperative analgesia have been shown to decrease postoperative pain control in nephrectomy patients, the three methods have never been compared to each other. This study aims to compare three different pain techniques proven to be beneficial in surgical nephrectomies, including the efficacy and the side effects …

  • 304 views
  • 04 Mar, 2022
  • 1 location
Quadratus Lumborum vs Erector Spinae Supplementary Blocks With Lumbar Plexus Blocks for Hip PAO

This study proposes to evaluate the efficacy of single shot erector spinae block (ESB) versus single shot quadratus lumborum block (QLB) when used in conjunction with continuous lumbar plexus block (LPB) for postoperative analgesia in children and adolescents undergoing unilateral hip surgical procedures. The aim of this study is to …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression (CREST-MST)

This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for depression. Even with multiple medication trials, 30 - 40% of patients will experience a pharmacologically resistant form of illness. The ineffectiveness of current treatments for major depressive disorder …

psychosis
remission
depression
convulsive therapy
antidepressants
  • 389 views
  • 07 Oct, 2022
  • 2 locations
Incorporating Supersaturated Oxygen in Shock (ISO-SHOCK)

A multi-center, prospective randomized (1:1) pilot and feasibility study to evaluate the safety and feasibility of supersaturated oxygen (SSO2) therapy delivered for 60 minutes selectively into the culprit coronary artery of patients presenting with ST elevation myocardial infarction and cardiogenic shock (STEMI-CS) treated using a shock protocol.

  • 0 views
  • 07 Oct, 2022
  • 5 locations
3D-Printed Patient-Specific Surgical Plates Versus Conventional Surgical Plates in Jaw Reconstruction

Objectives: The aim of this randomised controlled clinical trial is to evaluate surgical accuracy and efficiency of computer-assisted jaw reconstruction using 3D-printed patient-specific titanium surgical plates versus conventional plates. Hypothesis to be tested: The investigators hypothesize that compared to conventional surgical plates, 3D-printed patient-specific surgical plates improve surgical accuracy and …

  • 0 views
  • 16 Apr, 2021
  • 1 location
Connettive Tissue Graft Versus Collagen Matrix.

Despite the potential role of soft tissue thickness in maintaining gingival margin stability, the existing literature has mainly focused on investigating the effect of different surgical techniques on recession coverage percentage, without taking into account the changes in tissue thickness and biotype in the surgical area. Hence, this study aims …

Accepts healthy volunteers
  • 0 views
  • 14 May, 2022
  • 1 location
"Surgical vs. Non-surgical Peri-implant Therapy"

The aim of this randomized clinical trial is to evaluate the effectiveness, in terms of clinical and radiographic changes, of non-surgical peri-implant therapy (mechanical/chemical) versus regenerative surgical therapy (xenograft and collagen membrane), after a follow-up period of 12 months.

debridement
Accepts healthy volunteers
  • 0 views
  • 12 Mar, 2022
  • 1 location