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Found 64 clinical trials
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Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

Background: People are living longer and are more likely to survive a heart attack if they have one. Longer life expectancy is good but it also means more people get chronic heart failure over time. This is a condition in which the heart doesn't pump blood as well as it …

heart failure
radionuclide ventriculography
cardiopulmonary exercise testing
systolic heart failure
chronic heart failure
  • 311 views
  • 09 Apr, 2019
  • 1 location
A Phase 2b, Open-label, Single Dose Study to Evaluated the Safety and Efficacy of RT234 on Exercise Parameters Assessed by Cardiopulmonary Exercise Testing (CPET) in Subjects With Pulmonary Arterial Hypertension (PAH) (VIPAH-PRN 2B)

The objectives of this study are to evaluate the effects of RT234 on exercise parameters assessed by a specialized exercise test (Cardiopulmonary Exercise Test or CPET) in patients with

cpet
right heart catheterization
exercise test
epoprostenol
calcium channel blockers
  • 0 views
  • 19 Sep, 2022
  • 12 locations
Step, Walk, Bike: Comparisons of Fitness Assessments

test, 6 MWT) with maximal exercise test (cardiopulmonary exercise test, CPET)

Accepts healthy volunteers
  • 0 views
  • 04 May, 2022
  • 1 location
Effects of IMT on Functional Capacity in Patients With Chronic COVID After Hospital Discharge (InsCOVID)

exercise testing (CPET) at 12-week. Patients with chronic COVID (>3 months) after hospital discharge will be enrolled. A sample size estimation [alfa: 0.05, power: 80%, a 15% loss rate, and at least a

  • 0 views
  • 23 Apr, 2022
  • 1 location
8-Weeks of High-Intensity Interval Training or Concurrent Training in Overweight and Obese Adult Males

Overweight and obesity is becoming increasingly prevalent, constituting 64% of all adults in England, causing an incessant rise in cost to the National Health Service. Exercise and physical activity have the potential to reduce incidence of overweight and obesity, as well as improve obesity-related ill health. However, overweight and obese …

Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 1 location
The Effect Custom Foot Orthotics on Comfort, Kinetics and Kinematics

The overarching aim of this project is to investigate the role of custom foot orthotics in a 'return to performance' framework as the ultimate part of the 'return to sport continuum'. The aim of this particular study is to investigate the effect of Custom Foot Orthotics (CFO) made from different …

Accepts healthy volunteers
  • 0 views
  • 13 Jun, 2022
  • 1 location
VLCD & Adjuvant Exercise Effect in Overweight Diabetic Men (VLCDeXDM)

Sarcopenia is defined as the incremental age-related loss of skeletal muscle in humans which generally begins from forty years old. It is associated with an overall reduction in quality of life and increased morbidity and mortality. Patients with type two diabetes mellitus (T2DM) are particularly at risk of developing sarcopenia, …

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH (CAPACITY)

cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

stress test
exercise stress test
ralinepag
diuretics
cardiopulmonary exercise testing
  • 4 views
  • 04 Oct, 2022
  • 36 locations
Exercise Testing in Diseases and Health

Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population. CPET provides a full assessment of the physiologic

Accepts healthy volunteers
  • 0 views
  • 13 Apr, 2022
  • 1 location
Post Cardiac Valvular Surgery Rehabilitation (PORT)

The incidence of adult rheumatic valvular heart disease is 2.34% to 2.72% in China. Although guidelines or consensus recommendations recommend rehabilitation after valve surgery, clinical studies are still lacking, especially for Chinese patients. Current limited clinical studies focus mainly on physical capacity and self-assessed mental health. The investigators hope to …

educational intervention
exercise test
valvular disease
heart disease
rehabilitation program
  • 16 views
  • 15 Feb, 2022
  • 1 location